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Page d'accueilToutes les moléculesCLEC4C
CLEC4C
CLEC4C Informations sur la molécule
| Nom anglais | C-Type lectin domain family 4 member C | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 9 | Alias de la cible | DLEC，HECL，C-type lectin superfamily member 7，CLEC4C，BDCA2，UNQ9361/PRO34150，C-type lectin domain family 4 member C，Dendritic lectin，C-Type (Calcium Dependent， Carbohydrate-Recognition Domain) Lectin， Superfamily Member 7，C-Type Lectin Domain Family 4， Member C，CLECSF11，CLECSF7，BDCA-2，C-Type (Calcium Dependent， Carbohydrate-Recognition Domain) Lectin， Superfamily Member 11，Blood Dendritic Cell Antigen 2 Protein，Blood Dendritic Cell Antigen 2，Dendritic Cell Lectin B，CD303 Antigen，PRO34150，CD303 |
| Phase de R&D la plus avancée | Phase 3 Clinical | ||
| Nom anglais | C-Type lectin domain family 4 member C |
| Alias de la cible | DLEC，HECL，C-type lectin superfamily member 7，CLEC4C，BDCA2，UNQ9361/PRO34150，C-type lectin domain family 4 member C，Dendritic lectin，C-Type (Calcium Dependent， Carbohydrate-Recognition Domain) Lectin， Superfamily Member 7，C-Type Lectin Domain Family 4， Member C，CLECSF11，CLECSF7，BDCA-2，C-Type (Calcium Dependent， Carbohydrate-Recognition Domain) Lectin， Superfamily Member 11，Blood Dendritic Cell Antigen 2 Protein，Blood Dendritic Cell Antigen 2，Dendritic Cell Lectin B，CD303 Antigen，PRO34150，CD303 |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 9 |
| Phase de R&D la plus avancée | Phase 3 Clinical |
CLEC4C Liste de produits
- Attribut
Protein (6)
- Bibliothèque de produits
En ligne (6)
- Espèces
Human (3)Cynomolgus (3)
- Étiquette
Fc Tag (2)His Tag (2)His Tag & Avi Tag (2)
- Marqueur
Unconjugated (4)Biotin-labeled (2)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
HOT CLC-H5245 |  Human | HEK293 | Human CLEC4C / BDCA2 Protein, His Tag |  |  |  |  Ajouter au panier |
CLC-H5254 | Human | HEK293 | Human CLEC4C / BDCA2 Protein, Fc Tag |  | | | Ajouter au panier |
CLC-H82Q3 | Human | HEK293 | Biotinylated Human CLEC4C / BDCA2 Protein, Avitag™,His Tag |  | | | Ajouter au panier |
CLC-C5253 |  Cynomolgus | HEK293 | Cynomolgus CLEC4C / BDCA2 Protein, Fc Tag (MALS verified) |  | | | Ajouter au panier |
CLC-C52H4 | Cynomolgus | HEK293 | Cynomolgus CLEC4C / BDCA2 Protein, His Tag (MALS verified) |  | | | Ajouter au panier |
CLC-C82Q3 | Cynomolgus | HEK293 | Biotinylated Cynomolgus CLEC4C / BDCA2 Protein, Avitag™,His Tag |  | | | Ajouter au panier |
Quantité totale6
- 1
CLEC4CContexte de la molécule
CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
CLEC4CAlias de la molécule
DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| Litifilimab | BIIB-059 | Phase 3 Clinical | Biogen Inc | Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic | Details |
| SSGJ-626 | SSGJ-626; 626 | Phase 2 Clinical | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic | Details |
| DB-2304 | DB-2304 | Phase 2 Clinical | Duality Biologics (Suzhou) Co Ltd | Autoimmune Diseases; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic | Details |
| ANB-101 | CBS-004; ANB101 | Phase 1 Clinical | Capella Bioscience Ltd | Inflammation; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Scleroderma, Systemic | Details |
| BCD-256 | BCD-256 | Phase 1 Clinical | BIOCAD JSC | Lupus Erythematosus, Systemic | Details |
| GB-19 | GB-19; GB19 | Phase 1 Clinical | Shandong Kexing Bio-Products Co Ltd | Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic | Details |
| Recombinant anti-BDCA2 humanized monoclonal antibody (Sansheng Guojian) | Phase 1 Clinical | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic | Details | |
| HC-022 | HC-022; HC022 | Phase 1 Clinical | Shanghai Hongcheng Pharmaceutical Co Ltd | Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic | Details |
| LBL-047 | DNTH-212; LBL-047; DNTH212 | Phase 1 Clinical | Nanjing Leadsbiolabs Co Ltd | Autoimmune Diseases; Lupus Erythematosus, Systemic | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments cliniques
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