SCARB1

SCARB1 Informations sur la molécule

Nom anglais	Scavenger receptor class B member 1	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	CLA1，SRB1，SCARB1，Scavenger Receptor Class B Member 1，CD36 Antigen (Collagen Type I Receptor， Thrombospondin Receptor)-Like 1，CD36 And LIMPII Analogous 1，CD36L1，CLA-1，SR-BI，Collagen Type I Receptor， Thrombospondin Receptor-Like 1，Scavenger Receptor Class B， Member 1，Scavenger Receptor Class B Type III，CD36 Antigen-Like 1，HDLQTL6
Phase de R&D la plus avancée	Preclinical

Nom anglais	Scavenger receptor class B member 1
Alias de la cible	CLA1，SRB1，SCARB1，Scavenger Receptor Class B Member 1，CD36 Antigen (Collagen Type I Receptor， Thrombospondin Receptor)-Like 1，CD36 And LIMPII Analogous 1，CD36L1，CLA-1，SR-BI，Collagen Type I Receptor， Thrombospondin Receptor-Like 1，Scavenger Receptor Class B， Member 1，Scavenger Receptor Class B Type III，CD36 Antigen-Like 1，HDLQTL6
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Preclinical

SCARB1 Liste de produits

Attribut
Protein (2)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
Fc Tag (1)His Tag & Avi Tag (1)
Marqueur
Unconjugated (1)Biotin-labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
SC1-H5258	Human	HEK293	Human SCARB1 / SR-B1 Protein, Fc Tag				Ajouter au panier
SC1-H82E5	Human	HEK293	Biotinylated Human SCARB1 / SR-B1 Protein, His,Avitag™ (MALS verified)				Ajouter au panier

Quantité totale2

SCARB1Contexte de la molécule

Scavenger receptor class B member 1 (SRB1) is also known as SR-BI, CD36 and LIMPII analogous 1 (CD36L1), CLA-1, is a member of the scavenger receptor family or CD36 family. CD36L1 is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. SRB1 is receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. CLA-1 facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high-density lipoprotein (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. SCARB1 is, along with CD81, the receptor for the entry of the Hepatitis C virus glycoprotein E2 in liver cells, and binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. SRB1 plays an important role in the uptake of HDL cholesteryl ester.