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Monoclonal Anti-Fusion glycoprotein F0 Antibody, Mouse IgG2a (101F)

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RSF-M309a-100ug
$415.00
In Stock - Delivery in 2-3 business days
RSF-M309a-1mg
$2735.00
In Stock - Delivery in 2 weeks
Total des articles Montant du produit$ 0

Détails du produit

  • Source

    Chimeric Monoclonal Anti-Fusion glycoprotein F0 Antibody, Mouse IgG2a (101F) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to mouse IgG2a constant domains.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    101F

  • Isotype

    Mouse IgG2a, Kappa

  • Host Species

    Mouse

  • Specificity

    This product is a specific antibody specifically reacts with RSV-F0.

  • Application

    Application
    Recommended Use / Performance
    ELISA
    0.2-2 μg/mL
  • Cross Verification

    This product can cross in Western Blot with
    HRSV (A) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H6).
    HRSV (A) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H7).
    HRSV (B) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H9).
    HRSV (B) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H8).

  • Purification

    Protein A purified.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Affichage des données

  • Bioactivity-ELISA

     Fusion glycoprotein F0/F protein (RSV) ELISA

    Immobilized HRSV (A) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H6) at 2 μg/mL (100 μL/well) can bind Anti-Fusion glycoprotein F0 Antibody, Mouse IgG2a (101F) (Cat. No. RSF-M309a) with a linear range of 0.2-10 ng/mL (QC tested).

    Protocol
  •  Fusion glycoprotein F0/F protein (RSV) ELISA

    Immobilized HRSV (A) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H7) at 2 μg/mL (100 μL/well) can bind Anti-Fusion glycoprotein F0 Antibody, Mouse IgG2a (101F) (Cat. No. RSF-M309a) with a linear range of 0.2-10 ng/mL (QC tested).

    Protocol

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FAQ

  • product

    Can lyophilized proteins remain stable during room-temperature shipping or temporary room-temperature exposure?

    In general, lyophilized proteins remain stable during room-temperature shipping or temporary exposure to room-temperature conditions.


    Many ACROBiosystems recombinant proteins are supplied in lyophilized (freeze-dried) form. The lyophilization process effectively removes moisture from the product, helping reduce degradation-related reactions and improve protein stability during transportation and storage.


    To evaluate the stability of lyophilized proteins under normal temperature conditions, ACROBiosystems conducted a stability study on 11 representative lyophilized protein products at 37°C. The study demonstrated that these proteins maintained good quality stability after storage at 37°C for approximately 20 days. Based on these validation results, temporary room-temperature exposure during shipping or handling is generally not expected to have a significant impact on product quality or downstream application performance.


    To ensure optimal long-term stability, products should be stored according to the storage conditions specified in the product Certificate of Analysis (COA) upon receipt.


    Supporting Document


Introduction de fond

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation. Antibody 101F, target epitopes that have been mapped to linear regions in the F1 subunit, referred to as antigenic site IV.

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