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Background
Recombinant Monoclonal Anti-HER3 Antibody, Rabbit (5B6) is a HER3 primary antibody for IHC application. HER3 is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family. HER3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon.
Product Specifications
Host SpeciesRabbitIsotypeRabbit IgG, Rabbit KappaClone5B6ApplicationIHC-PDilution Ratio1: 500 - 1: 2000FormLiquidClonalityMonoclonalReactivityHumanSynonymsERBB3Concentration0.9~1.1 mg/mlSpecificityReact with HER3 protein on the membrane of target cell/tissuePurification TechProtein APreservationPBS, BSA, GlycerolExperiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.ACRO Quality Management System
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Sample Staining Data
Immunohistochemical analysis of paraffin embedded human colorectal cancer labelled with HGS-S405 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
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