GENPower™ LbCas12a Nuclease (2.5 μg/μL), low endotoxin (MALS verified)

GENPower™ LbCas12a Nuclease (2.5 μg/μL) is a recombinant Lachnospiraceae bacterium Cas12 protein purified from Escherichia coli for CRISPR-based genome editing. The introduction of nuclear localization signals (NLS) can help Cas12 enter the nucleus, increasing the chance of genomic DNA cleavage.

• With two NLS, which leads to transport to the nucleus efficiently.
• High cleavage activity.

Developed as a variety of genome editing tools, such as transcription regulation, gene recombination, and base editing.

2.5 μg/μL

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

Negative

Less than 0.01 EU per μg by the LAL method / rFC method.

Supplied as 0.2 μm filtered solution in 20 mM NaAC, 500 mM NaCl, pH6.0 with glycerol as protectant.

Contact us for customized product form or formulation.

This product is supplied and shipped on dry ice.

• The product MUST be stored at -20°C or lower upon receipt;
• -20°C for 3 months under sterile conditions.