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PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein

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Numéro de produit/spécification
Prix
Qté
HLV-HP2H8-25ug
$410.00
HLV-HP2H8-200ug (100ug X 2)
$2350.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Synonyms

    HLA-A*0301 & B2M & KRASG12V (VVGAVGVGK)

  • Source

    PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein (HLV-HP2H8) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGAVGVGK peptide (Accession # P04439-1 (HLA-A*03:01) & P61769 (B2M) & VVGAVGVGK).

    Predicted N-terminus: Ile 21

    Request for sequence
  • Molecular Characterization

    PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein is assembled by biotinylated monomer (HLV-H82E9) and PE-labeled streptavidin.

    Biotinylated Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. Biotinylated Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 1% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Introduction de fond

The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Biotinylated Human HLA-A*0301 KRASG12V (VVGAVGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVGAVGVGK peptide of the KRASG12V.

Progrès de frontière

 
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