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Human IRAK4 Protein, GST Tag (active enzyme, HPLC verified)

AIDD‑Ready
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IR4-H5533-100ug
$399.00
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IR4-H5533-1mg
$2,940.00
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IR4-H5533
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Synonyms

IMD67, IPD1, IRAK-4, NY-REN-64, REN64

Source

Human IRAK4 Protein, GST Tag (IR4-H5533) is expressed from Baculovirus-Insect cells. It contains AA Asn 2 - Ser 460 (Accession # Q9NWZ3-1).

Predicted N-terminus: Met

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a GST tag at the N-terminus.

The protein has a calculated MW of 76.9 kDa. The protein migrates as 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 50 mM HEPES, 300 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

Introduction de fond

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.