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Détails du produit
Synonyms
OX40L, TNFSF4, CD252, Glycoprotein Gp34, TXGP1, CD134 ligand, CD134L
Source
Rat OX40 Ligand, His Tag (OXL-R5248) is expressed from human 293 cells (HEK293). It contains AA Gln 49 - Leu 199 (Accession # Q9Z2P3-1).
Predicted N-terminus: His
Molecular Characterization
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 53.8 kDa. The protein migrates as 58-68 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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Affichage des données
SDS-PAGE
Rat OX40 Ligand, His Tag on SDS-PAGE under non-reducing (NR) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS
The purity of Rat OX40 Ligand, His Tag (Cat. No. OXL-R5248) is more than 85% and the molecular weight of this protein is around 55-70 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Rat OX40, Fc Tag (Cat. No. OX0-R5253) at 2 μg/mL (100 μL/well) can bind Rat OX40 Ligand, His Tag (Cat. No. OXL-R5248) with a linear range of 20-78 ng/mL (QC tested).
Protocol
Immobilized Rat OX40 Ligand, His Tag (Cat. No. OXL-R5248) at 2 μg/mL (100 μL/well) can bind Rat OX40, Fc Tag (Cat. No. OX0-R5253) with a linear range of 0.2-5 ng/mL (Routinely tested).
Protocol
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Introduction de fond
Progrès de frontière
Progrès du développement médicamenteux- Nom anglais：
Tumor necrosis factor ligand superfamily member 4
- Catégorie：
- Nombre de médicaments répertoriés：
0 Détails
- Nombre de médicaments cliniques：
13 Détails
- Étape de développement la plus élevée：
Phase 3 Clinical
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