CXCL9

CXCL9 Informations sur la molécule

Nom anglais	C-X-C motif chemokine 9	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1	Alias de la cible	C-X-C motif chemokine 9，Gamma-interferon-induced monokine，Monokine induced by interferon-gamma (HuMIG; MIG)，Small-inducible cytokine B9，SCYB9，Crg-10，Humig，CMK，MIG，Monokine Induced By Gamma Interferon，Monokine Induced By Interferon-Gamma，Gamma-Interferon-Induced Monokine，Chemokine (C-X-C Motif) Ligand 9，Small-Inducible Cytokine B9，C-X-C Motif Chemokine 9，HuMIG
Phase de R&D la plus avancée	Phase 1 Clinical

Nom anglais	C-X-C motif chemokine 9
Alias de la cible	C-X-C motif chemokine 9，Gamma-interferon-induced monokine，Monokine induced by interferon-gamma (HuMIG; MIG)，Small-inducible cytokine B9，SCYB9，Crg-10，Humig，CMK，MIG，Monokine Induced By Gamma Interferon，Monokine Induced By Interferon-Gamma，Gamma-Interferon-Induced Monokine，Chemokine (C-X-C Motif) Ligand 9，Small-Inducible Cytokine B9，C-X-C Motif Chemokine 9，HuMIG
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1
Phase de R&D la plus avancée	Phase 1 Clinical

Demande de produit

CXCL9Contexte de la molécule

CXCL9 is a small cytokine belonging to the CXC chemokine family that is also known as monokine induced by gamma interferon (MIG). CXCL9 is a chemokine that plays a role in immune responses, it can induce chemotaxis, promote differentiation and proliferation of leukocytes, and cause tissue extravasation. CXCL9 regulates immune cell migration, differentiation and activation by binding to CXCR3 receptor, such as CTLs, NK cells, NKT cells and macrophages. CXCL9 also participates in Th1 polarization and IFN-γ response.

CXCL9Alias de la molécule

CMK, Humig, MIG, SCYB9, crg-10

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
NG-641	EnAd-FAP-BiTE; EnAd-FAP-Tac; NG-641; NG-aFAP	Phase 1 Clinical	Akamis Bio Ltd, University Of Oxford	Squamous Cell Carcinoma of Head and Neck; Neoplasms, Glandular and Epithelial; Neoplasm Metastasis	Details