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Core reagents for infectious disease research
Infectious diseases are caused by various pathogens, including viruses, bacteria, fungi, or parasites. These diseases can spread from person-to-person by direct contact, water, foodborne illness, or aerosolization of infected particles in the environment and through insects (mosquitoes) and ticks.
In late 2019, the SARS-COV-2 pandemic posed a serious threat to human health and social-economic development. Looking back to human history, several kinds of infectious diseases, such as smallpox, plague, and Spanish flu, all made huge impacts on human society. Until now, influenza virus, rabies virus, respiratory syncytial virus, human papillomavirus and many other infectious viruses are still constantly threatening the safety of our life. Therefore, now current scientific and medical industry is focusing to develop safe and effective vaccines and drugs to prevent and treat infectious diseases.
ACROBiosystems has accumulated mature technology and experience in viruses and vaccines. Since the COVID-19 outbreak, we continued to develop core reagents for other infectious virus research, vaccine, and therapeutic drug development based on its high-quality platform. We will continue to monitor the development of infectious diseases worldwide, aiming to provide core reagents for accelerating the development and clinical trials of vaccines and therapeutic drugs.
Viruses of Concern
Main Features
HEK293 expression: the protein structure is closer to the natural conformation;
High purity verified by SDS-PAGE and MALS;
High Bioactivity verified by antigen-antibody or antigen-receptor binding experiments;
High immunogenicity, which can induce higher antibody titers;
It can be used for drug screening and vaccine development.
Which viral pathogens are covered by the infectious-disease reagent collection?
The collection spans RSV, influenza, VZV, MPXV, HIV, rabies, HSV, Nipah, Hendra, Zika, dengue and many additional listed viruses. Availability differs by pathogen.
Q
What product types can I find for infectious-disease research?
Depending on the virus, the range can include recombinant antigens or proteins, monoclonal antibodies and assay kits. Check the pathogen-specific listing rather than assuming every product type is available for every virus.
Q
How should I select a viral antigen for an assay?
Match the virus, strain or subtype, viral protein, conformational state, tag and intended assay. For conformation-sensitive targets, select products explicitly named as pre-fusion, post-fusion, trimeric or tetrameric when required.
Q
Are both pre-fusion and post-fusion RSV F proteins represented?
Yes. RSV products include pre-fusion and post-fusion F proteins, along with RSV A and B G proteins and selected antibodies or kits directed at these antigens.
Q
Can I select influenza antigens by strain and subtype?
Yes. The influenza range lists strain- and subtype-specific proteins, including HA, NA and other antigens. Match the catalog entry to the exact strain or lineage required by the study.
Q
Which VZV antigens are available for vaccine-related studies?
The VZV range includes gE and gH/gL products, with additional antigen, antibody and ELISA options listed in the dedicated VZV solution.
Q
Are SEC-MALS, SDS-PAGE and functional data available for all viral reagents?
No. These data are displayed for selected products. Review the individual product record for purity, oligomeric-state and antigen–antibody or receptor-binding evidence.
Q
Can the collection support both vaccine and antiviral-drug research?
Yes. The listed antigens, antibodies and assay kits cover use cases such as antigen characterization, immune-response measurement, binding studies and screening. Suitability depends on the specific reagent and assay evidence.