HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (MALS verified)

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GLD-V52H3-50ug
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Synonyms

Glycoprotein D/gD (HSV)

Source

HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (GLD-V52H3) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Thr 310 (Accession # Q69091-1).

Predicted N-terminus: Lys 26

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 33.5 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

Background

Herpes simplex virus type 1 (HSV‑1) glycoprotein D (gD) is an essential envelope protein required for viral entry. By binding host receptors such as nectin‑1, gD triggers the membrane‑fusion cascade that allows HSV‑1 to penetrate cells. Neutralizing antibodies targeting gD can block receptor engagement and inhibit infection.