Gastrin-71

Gastrin-71 Informations sur la molécule

Nom anglais	Gastrins	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	Gastrins
Phase de R&D la plus avancée	Discontinued

Nom anglais	Gastrins
Alias de la cible	Gastrins
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Discontinued

Demande de produit

Gastrin-71Contexte de la molécule

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which in turn increases H+ release into the stomach cavity). Its release is stimulated by peptides in the lumen of the stomach.