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HLA-A*02:01 & B2M & WT-1 (RMFPNAPYL)

HLA-A*02:01 & B2M & WT-1 (RMFPNAPYL) Liste de produits

  • Attribut

    Protein (2)

  • Bibliothèque de produits

    En ligne (2)

  • Espèces

    Human (2)

  • Étiquette

    His Tag & Avi Tag (1)His Tag (1)

  • Marqueur

    Biotin-labeled (1)Unconjugated (1)

Numéro de produitEspècesSystème d'expressionDescription du produitStructure protéiquePuretéCaractéristiquesPré-commande/Commande
HLW-H52E6
Human
HEK293
Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein (MALS verified) Ajouter au panier
HLW-H82E5
Human
HEK293
Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein (Monomer, MALS verified) Ajouter au panier
Quantité totale2
  • 1

HLA-A*02:01 & B2M & WT-1 (RMFPNAPYL)Contexte de la molécule

Wilms tumor gene 1 (WT1),is an attractive target antigen for leukemia and solid cancer. WT1-specific adoptive immunotherapy has developed for tumor treatment in recent years. WT1 has been proved wildly expressed in breast, colon and ovarian cancer. It participates in cell growth, differentiation and apoptosis regulation. The WT1127-134 (RMFPNAPYL) was shown to be recognized by HLA-A*0201 tumor-infiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCR-T studies. The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1.
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