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Monoclonal Anti-C11D5.3 scFv Antibody, Mouse lgG1 (3G8C1) (Carrier-free) (recommended for ADA assay)

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C13-MY2010b-25ug
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C13-MY2010b-100ug
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C13-MY2010b
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Source

Monoclonal Anti-C11D5.3 scFv Antibody, Mouse lgG1 (3G8C1) (Carrier-free) (recommended for ADA assay) is a recombinant mouse monoclonal antibody expressed in HEK293 cells.

Antibody Type

Recombinant Monoclonal

Clone

3G8C1

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Mouse

Immunogen

Recombinant Mouse C11D5.3 scFv derived from HEK293 cells

Specificity

Specifically recognizes C11D5.3 derived CARs.

Application
Application
Recommended Use
ELISA
0.2-2 μg/mL

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Aggregation

Less than 10%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 12 months under sterile conditions.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Introduction de fond

C11D5.3 is an IgG1 mouse monoclonal antibody specific for BCMA, which is a target for the immunotherapy of multiple myeloma and lymphomas. C11D5.3 scFv is the most commonly used ectodomain componse of BCMA-specific CARs. So far, multiple reported CART BCMA trials contain the anti-BCMA scFv derived from C11D5.3, such as FDA approved CARs Abecma.