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PerCP-Cy5.5 Labeled Monoclonal Anti-Human CD45 Antibody, Mouse IgG2a (2E9) (0.03% Proclin)

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Numéro de produit/spécification
Prix
Qté
FABm056-06-100tests (50tests X 2)
$220.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Source

    Monoclonal Anti-Human CD45 Antibody, Mouse IgG2a (2E9) is a mouse monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    2E9

  • Isotype

    Mouse IgG2a, Kappa

  • Host Species

    Mouse

  • Reactivity

    Human

  • Immunogen

    Purified Human CD45 Protein

  • Conjugate

    PerCP-Cy5.5

    Excitation Wavelength: 488 nm

    Emission Wavelength: 690 nm

  • Specificity

    This product is a specific antibody specifically reacts with CD45 protein.

  • Application

    Flow Cytometry (Evaluation of the expression of CD45 on Human cells).

  • Recommended Dilution

    1:20

  • Form

    Liquid

  • Formulation

    Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Shipping

    Liquid product is shipped at blue ice.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Affichage des données

  • Bioactivity-FACS

     CD45 FACS

    Flow cytometric analysis of Jurkat staining with PerCP-Cy5.5 Labeled Monoclonal Anti-Human CD45 Antibody, Mouse IgG2a (2E9) (Cat. No. FABm056-06) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. Percp-cy5.5 signal was used to evaluate the binding activity (QC tested).

    Protocol

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Introduction de fond

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

Progrès de frontière

 
Progrès du développement médicamenteux
  • Nom anglais:

    Leukocyte common antigen

  • Catégorie:

  • Nombre de médicaments répertoriés:

    0 Détails

  • Nombre de médicaments cliniques:

    7 Détails

  • Étape de développement la plus élevée:

    Phase 3 Clinical

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