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APC-CY7-Labeled Monoclonal Anti-Human CD8 Antibody, Mouse IgG1

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FABm003-05-50tests
$180.00
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FABm003-05-200tests (50tests X 4)
$560.00
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FABm003-05
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Source

APC-CY7-Labeled Monoclonal Anti-Human CD8 Antibody, Mouse IgG1 is a recombinant mouse monoclonal antibody expressed in - cells.

Antibody Type

Recombinant Monoclonal

Clone

AS228

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Human

Conjugate

APC-CY7

Excitation Wavelength: 637 nm

Emission Wavelength: 780 nm

Specificity

This product is a specific antibody specifically reacts with CD8 protein.

Application
Application
Recommended Use
Flow Cytometry
1:20

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Store at 2-8 °C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.