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Biotinylated Monoclonal Anti-Enfortumab Antibody, Mouse IgG1 (7D10)

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Numéro de produit/spécification
Prix
Qté
ENB-BLMY2644-25ug
$415.00
ENB-BLMY2644-200ug
$1705.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Source

    Biotinylated Monoclonal Anti-Enfortumab Antibody, Mouse IgG1 (7D10) is a recombinant mouse monoclonal antibody expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    7D10

  • Isotype

    Mouse IgG1, Kappa

  • Host Species

    Mouse

  • Conjugate

    Biotin

  • Specificity

    Specifically recognizes Human Enfortumab; This antibody is a neutralizing antibody.

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 5%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Affichage des données

  • Bioactivity-ELISA

     Enfortumab ELISA

    Immobilized Monoclonal Anti-Enfortumab Antibody, Mouse IgG1 (7D6) (Cat. No. ENB-MY2483) at 5 μg/mL, add Enfortumab and then add Biotinylated Monoclonal Anti-Enfortumab Antibody, Mouse IgG1 (7D10) (Cat. No. ENB-BLMY2644) at 2 μg/mL. Detection was performed using HRP-conjugated Streptavidin (Acro, Cat. No. STN-NH913) (QC tested).

    Protocol

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Introduction de fond

Enfortumab, is a monoclonal antibody used to treat urothelial carcinoma. Specifically it is used for urothelial carcinoma that is Nectin-4 receptor positive. Enfortumab works by binding to the Nectin-4 receptor and inducing tumor cell apoptosis. Enfortumab is a recombinant IgG1 kappa, fully human monoclonal antibody that selectively binds with high affinity in a cell-based assay to the extracellular domain of the human Nectin-4 protein.

Progrès de frontière

 
Drug Candidate Licensing
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  • Informations de base sur le produit
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  • Les clients ont également consulté
  • Affichage des données
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