Save Product
Product Details
Background
Recombinant Monoclonal Anti-FAP Antibody, Rabbit (M1D4) is a FAP primary antibody for IHC application.
FAP is a type II transmembrane serine protease that is selectively expressed in activated fibroblasts during tissue remodeling, wound healing, and tumorigenesis. It functions at the cell surface and in the extracellular region, linking stromal activation to matrix remodeling. FAP supports tumor progression and is associated with cell invasion, angiogenesis, and immune evasion. FAP Expression measurements show high levels in hepatobiliary, renal, and female reproductive systems.Product Specifications
Host SpeciesRabbitIsotypeRabbit IgG, Rabbit KappaCloneM1D4ApplicationIHC-PDilution Ratio1: 100 - 1: 500FormLiquidClonalityMonoclonalReactivityHumanSynonymsfibroblast activation protein alphaConcentration0.9~1.1 mg/mlSpecificityReact with FAP protein on the membrane and intracellular area of target cell/tissuePurification TechFc-TagPreservationPBS, 11% Trehalose, 40% Glycerol, 0.03% Proclin 300, 0.05% BSA (pH7.3)Experiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.ACRO Quality Management System
Customers Also Viewed
Performance Data
Sample Staining Data
Immunohistochemical analysis of paraffin embedded human colorectal cancer labelled with HGS-M2720 at 1/150 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
Customer Reviews Writing Reviews
Recent Advances
Drug Development Progress- English Name：
Prolyl endopeptidase FAP
- Category：
- Approved Drugs：
0 Details
- Drugs in Clinical Trials：
88 Details
- Highest Development Stage：
Phase 3 Clinical
Contact Us
Drug Candidate Licensing