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Rabbit Anti-Mouse FMC63 Polyclonal Antibody (recommended for ADA assay) (MALS verified)

Numéro de produit/spécification
Prix
Qté
FM3-S93-100ug
$380.00
FM3-S93-1mg (100ug X 10)
$2715.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Source

    Rabbit Anti-Mouse FMC63 Polyclonal Antibody is a polyclonal antibody purified from rabbit serum.

  • Antibody Type

    Polyclonal Antibody

  • Host Species

    Rabbit

  • Reactivity

    Mouse

  • Immunogen

    FMC63 scFv

  • Specificity

    Recognizes FMC63 scFv specifically.

  • Application

    Application
    Recommended Usage
    ELISA
    0.2-2 μg/mL
  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 5%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Affichage des données

  • Bioactivity-ELISA

     FMC63 ELISA

    Immobilized FMC63 scFv, His Tag (Cat. No. CD9-M52Hb) at 2 μg/mL (100 μL/well) can bind Rabbit Anti-Mouse FMC63 Polyclonal Antibody (Cat. No. FM3-S93) with a linear range of 0.098-0.78 ng/mL (QC tested).

    Protocol
  •  FMC63 ELISA

    A microplate was coated with FMC63 monoclonal antibody, Mouse IgG2a, at 1 μg/mL. Serially diluted Rabbit Anti-Mouse FMC63 Polyclonal Antibody was added, followed by Biotinylated FMC63 scFv-Fc-Avitag at 2 μg/mL. Binding was detected using HRP-conjugated streptavidin. The QC-tested sensitivity was 78 ng/mL (QC tested).

    Protocol

Avis des utilisateurs
Publier un commentaire

  • S***n2024-07-16
    J'aime
    Work in logistics and these reagents were packaged well, delivered in a timely manner, and customer service has been extremely easy and fast to work with. Well organized company!

Introduction de fond

FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.

Progrès de frontière

 
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  • Informations de base sur le produit
  • Détails du produit
  • Les clients ont également consulté
  • Affichage des données
  • Avis des utilisateurs
  • Contexte