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HRP conjugated Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016)

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G4S-HLY25G1-25ug
$410.00
In Stock - Delivery in 1-2 business days
G4S-HLY25G1-200ug
$1,865.00
In Stock - Delivery in 1-2 business days
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Source

HRP conjugated Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) is a recombinant rabbit monoclonal antibody expressed in HEK293 cells.

Antibody Type

Recombinant Monoclonal

Clone

016

Isotype

Rabbit IgG, Kappa

Host Species

Rabbit

Reactivity

All

Conjugate

HRP conjugated

Application
Application
Recommended Use
ELISA
1:1000-1:10000

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4) containing 0.01% PF68, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

The G4S linker is emerged as the most common linking peptides for scFvs. It is composed of the repeated sequence (Gly-Gly-Gly-Gly-Ser) and commonly found as either a 15-mer (G4S)3 or 20-mer(G4S)4 within scFv fragments. The G4S linker has become an integral part of the vast majority of CARs as it links the VH and VL recognition domains of scFvs. The G4S linker is commonly used in CARs targeting solid tumor antigens, such as HER2 and CEA, while the whitlow/218 linker peptide is predominantly used in CAR constructs targeting hematological malignancies such as CD19 CAR products.