Product Details
Background
Recombinant Monoclonal Anti-MUC16 Antibody, Rabbit (M1D08) is a MUC16 primary antibody for IHC application.
MUC16 is a membrane-tethered mucin that contributes to a protective mucous barrier on epithelial surfaces. MUC16 supports cell adhesion and barrier-related functions through its heavily glycosylated extracellular region. It is localized to the plasma membrane and also detected in extracellular vesicles and the extracellular region. MUC16 expression is high in the respiratory system and female reproductive system.Product Specifications
Host SpeciesRabbitIsotypeRabbit IgG, Rabbit KappaCloneM1D08ApplicationIHC-PDilution Ratio1: 100 - 1: 500FormLiquidClonalityMonoclonalReactivityHumanSynonymsCA125Concentration0.9~1.1 mg/mlSpecificityReact with MUC16 protein on the membrane of target cell/tissuePurification TechFc-TagPreservationPBS, 11% Trehalose, 40% Glycerol, 0.03% Proclin 300, 0.05% BSA (pH7.3)Experiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.ACRO Quality Management System
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Performance Data
Sample Staining Data

Immunohistochemical analysis of paraffin embedded human ovarian cancer labelled with HGS-M2713 at 1/250 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
Immunohistochemical analysis of paraffin embedded human pancreatic cancer labelled with HGS-M2713 at 1/250 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
Immunohistochemical analysis of paraffin embedded human cervical cancer labelled with HGS-M2713 at 1/250 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
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