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Monoclonal NeuN/Rbfox3 Antibody, Mouse IgG1

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NE3-S454-20ul
$80.00
NE3-S454-100ul
$415.00
Total des articles Montant du produit$ 0

Détails du produit

  • Source

    Monoclonal NeuN/Rbfox3 Antibody, Mouse IgG1 is a mouse monoclonal antibody produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse.
    Gene Synonyms: Fox-3, Hrn, Hrnbp3, Rbfox3, NeuN, Neuna60, RNA binding protein, fox-1 homolog (C. elegans) 3.

  • Clone

    AS454

  • Isotype

    Mouse IgG1, Kappa

  • Host Species

    Mouse

  • Immunogen

    Mouse Rbfox3 peptide fused to GST

  • Specificity

    This product is a specific antibody specifically reacts with NeuN/Rbfox3.

  • Application

    Application
    Recommended Use / Performance
    IF
    1:500
  • Purification

    Protein A purified.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Liquid

  • Formulation

    Supplied a 0.22 μm-filtered solution in PBS containing 50 mM Glycine and 50 mM Tris, with 40% glycerol as protectant.

    Please contact us for customized product forms or formulations.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Shipped at -20°C. Store at -70°C for 12 months.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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  • Immunostaining

     NeuN/Rbfox3 IMMUNOSTAINING

    2D cell staining: Immunofluorescent staining (10X) of Cerebral Organoid-derived neurons (CIPO-BWL001K) labeling NeuN (Red) with purified NE3-S454 at 1:500 dilution. DAPI (blue) was used as nuclear counterstain.

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Introduction de fond

The neuronal nuclear protein (NeuN) is a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. NeuN emerges during early embryogenesis in postmitotic neuroblasts and remains in differentiating and terminally differentiated neurons throughout the whole subsequent ontogeny. NeuN localized in nuclei and perinuclear cytoplasm of most of the neurons in the central nervous system of mammals, has been widely used as a marker for post-mitotic neurons.

Gusel'nikova VV, Korzhevskiy DE. Acta Naturae. 2015;7(2):42-7. PMID: 26085943; PMCID: PMC4463411.

General Notes: FOR RESEARCH USE ONLY.

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