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Monoclonal Anti-Human NoV VP1 Antibody, Mouse IgG1 (5B4)

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Numéro de produit/spécification
Prix
Availability
Qté
NO1-MY2188-100ug
$350.00
In Stock - Delivery in 2-3 business days
NO1-MY2188-1mg (500ug X 2)
$2310.00
In Stock - Delivery in 2 weeks
Total des articles Montant du produit$ 0

Détails du produit

  • Source

    Chimeric Monoclonal Anti-Human NoV VP1 Antibody, Mouse IgG1 (5B4) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to mouse IgG1 constant domains.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    5B4

  • Isotype

    Mouse IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Virus

  • Immunogen

    Recombinant Norwalk Viruses (NoV)GII.6 (VLP) Protein is expressed from Yeast

  • Specificity

    Specific recognition of NoV(GII.6) protein.

  • Application

    Application
    Recommended Use / Performance
    ELISA
    0.2-2 μg/mL
  • Purification

    Protein A purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Affichage des données

  • Bioactivity-ELISA

     NoV VP1 ELISA

    Immobilized Human NoV(GII.6)VP1 at 0.2ug/well (100 μL/well) can bind Monoclonal Anti-Human NoV VP1 Antibody, Mouse IgG1 (5B4) (Cat. No. NO1-MY2188) with a linear range of 0.10-6.25 ng/mL (QC tested).

    Protocol

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FAQ

  • product

    Can lyophilized proteins remain stable during room-temperature shipping or temporary room-temperature exposure?

    In general, lyophilized proteins remain stable during room-temperature shipping or temporary exposure to room-temperature conditions.


    Many ACROBiosystems recombinant proteins are supplied in lyophilized (freeze-dried) form. The lyophilization process effectively removes moisture from the product, helping reduce degradation-related reactions and improve protein stability during transportation and storage.


    To evaluate the stability of lyophilized proteins under normal temperature conditions, ACROBiosystems conducted a stability study on 11 representative lyophilized protein products at 37°C. The study demonstrated that these proteins maintained good quality stability after storage at 37°C for approximately 20 days. Based on these validation results, temporary room-temperature exposure during shipping or handling is generally not expected to have a significant impact on product quality or downstream application performance.


    To ensure optimal long-term stability, products should be stored according to the storage conditions specified in the product Certificate of Analysis (COA) upon receipt.


    Supporting Document


Introduction de fond

Noroviruses are icosahedral viruses in the family Caliciviridae, with a single-stranded, positive-sense RNA genome. Noroviruses are genetically diverse and can infect a wide variety of hosts. Norovirus is a leading cause of acute gastroenteritis (AGE) globally. They are divided into 10 genogroups (GI to GX) based on VP1 amino acid sequence. Each genogroup is subdivided into genotypes based on capsid amino acid sequence, with 49 genotypes currently described. Noroviruses can also be classified based on their RdRp (“polymerase”) sequence, with at least 60 P-types currently circulating.

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