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Détails du produit
Synonyms
ACE-2, ACEH, ACE2
Source
Biotinylated Human ACE2, Fc,Avitag (AC2-H82F9) is expressed from human 293 cells (HEK293). It contains AA Gln 18 - Ser 740 (Accession # Q9BYF1-1).
Predicted N-terminus: Gln 18
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™).
The protein has a calculated MW of 111.7 kDa. The protein migrates as 125-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Labeling
Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
Protein Ratio
Passed as determined by the HABA assay / binding ELISA.
Purity
>95% as determined by SDS-PAGE.
Formulation
Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.
Contact us for customized product form or formulation.
Shipping and Storage
This product is supplied and shipped on dry ice.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- The product MUST be stored at -70°C or lower upon receipt;
- -70°C for 3 months under sterile conditions.
ACRO Quality Management System
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Affichage des données
SDS-PAGE
Biotinylated Human ACE2, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-BLI
Loaded Biotinylated Human ACE2, Fc,Avitag (Cat. No. AC2-H82F9) on SA Biosensor, can bind SARS-CoV-2 S protein RBD, His Tag (Cat. No. SPD-C52H3) with an affinity constant of 31.9 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Protocol
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F***a2021-08-18
J'aimeBiotinylated Human ACE2 / ACEH Protein, Fc,Avitag have been instrumental in developing a multiplex based antibody detection and neutralization assay.
Introduction de fond
Progrès de frontière
Progrès du développement médicamenteux- Nom anglais：
Angiotensin-converting enzyme 2
- Catégorie：
- Nombre de médicaments répertoriés：
0 Détails
- Nombre de médicaments cliniques：
7 Détails
- Étape de développement la plus élevée：
Phase 2 Clinical
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