Human ENO1 Protein, His Tag (HPLC verified)

Numéro de produit/spécification
Prix
Availability
Qté
EN1-H5143-100ug
$350.00
In Stock - Delivery in 1-2 business days
EN1-H5143-1mg
$2,500.00
In Stock - Delivery in 1-2 business days
EN1-H5143
Montant du produit :
$ 0
0
Ajouter au panier
Suggestion de nouveau produit Request Quote
Contact Us
Contact Us
Montant du produit:
$ 0
0
Ajouter au panier
  • Détails du produit
  • Affichage des données
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

Enolase 1, ENO1, 2-phosphoglycerate dehydratase, ENO1L1

Source

Human ENO1 Protein, His Tag (EN1-H5143) is expressed from E. coli cells. It contains AA Ser 2 - Lys 434 (Accession # P06733-1).

Predicted N-terminus: Met

Molecular Characterization

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 49.1 kDa. The protein migrates as 50-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>90% as determined by SEC-HPLC.

Formulation

Supplied as 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH8.0 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.

Introduction de fond

Enolase 1 (ENO1), also known as alpha‑enolase, is a glycolytic enzyme that catalyzes the conversion of 2‑phosphoglycerate to phosphoenolpyruvate. It is ubiquitously expressed and accounts for the majority of cytosolic enolase activity. Beyond its metabolic role, ENO1 is a multifunctional “moonlighting” protein: on the cell surface it acts as a plasminogen receptor promoting extracellular matrix degradation and tumor invasion, while a nuclear isoform (MBP‑1) binds the c‑MYC promoter and regulates transcription. Overexpression of ENO1 has been linked to cancer progression, autoimmune diseases, and neurodegeneration, making it both a biomarker and a potential therapeutic target.