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FGF-6,Fibroblast growth factor 6,HST-2,HBGF-6
Human FGF-6, His Tag (FG6-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 38 - Ile 208 (Accession # P10767-1).
Predicted N-terminus: Ser 38
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 21 kDa.
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Fibroblast growth factor 6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. For instance, FGF-6 might involve in MSCs proliferation and chondrogenic differentiation. Additionally, FGF-6 were identified as oncogene products. FGF6 is found over expressed in prostatic intraepithelial neoplasia and prostate cancer and promotes the proliferation of the transformed prostatic epithelial cells.