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Détails du produit
Synonyms
GAS6, GAS-6, AXLLG
Source
Human GAS6 Protein, His Tag (GA6-H5246) is expressed from human 293 cells (HEK293). It contains AA Ala 49 - Ala 678 (Accession # Q14393-2).
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 71.8 kDa. The protein migrates as 80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
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Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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Affichage des données
SDS-PAGE
Human GAS6 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
Bioactivity-ELISA
Immobilized Human GAS6 Protein, His Tag (Cat. No. GA6-H5246) at 5 μg/mL (100 μL/well) can bind Human Axl, Fc Tag (Cat. No. AXL-H5253) with a linear range of 0.06-1 ng/mL (QC tested).
Protocol
Immobilized Human GAS6 Protein, His Tag (Cat. No. GA6-H5246) at 10 μg/mL (100 μL/well) can bind Human TYRO3, Fc Tag (Cat. No. TY3-H5251) with a linear range of 2-20 ng/mL (Routinely tested).
Protocol
Immobilized Human GAS6 Protein, His Tag (Cat. No. GA6-H5246) at 10 μg/mL (100 μL/well) can bind Human MERTK, Fc Tag (Cat. No. MEK-H5253) with a linear range of 0.04-1.3 μg/mL (Routinely tested).
Protocol
Bioactivity-SPR
Human Axl, Fc Tag (Cat. No. AXL-H5253) captured on Protein A Chip can bind Human GAS6 Protein, His Tag (Cat. No. GA6-H5246) with an affinity constant of 38.6 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Protocol
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Introduction de fond
Progrès de frontière
Progrès du développement médicamenteux- Nom anglais：
Growth arrest-specific protein 6
- Catégorie：
- Nombre de médicaments répertoriés：
0 Détails
- Nombre de médicaments cliniques：
1 Détails
- Étape de développement la plus élevée：
Phase 3 Clinical
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