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Biotinylated Human IL-18 R beta / IL-1 R7 Protein, His,Avitag™

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Numéro de produit/spécification
Prix
Qté
ILB-H82E8-25ug
$360.00
ILB-H82E8-200ug
$1420.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Synonyms

    IL-18 R beta, IL-1 R7, CD218b, CDw218b, IL-1 R7, IL-18 R beta, IL-18 receptor accessory protein, IL-18 receptor beta, IL18R beta, IL-18RAcP

  • Source

    Biotinylated Human IL-18 R beta, His,Avitag (ILB-H82E8) is expressed from human 293 cells (HEK293). It contains AA Phe 20 - Arg 356 (Accession # O95256-1).

    Predicted N-terminus: Phe 20

    Request for sequence
  • Molecular Characterization

    IL-18 R beta Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 42.0 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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  • SDS-PAGE

    IL-18 R beta SDS-PAGE

    Biotinylated Human IL-18 R beta, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

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Introduction de fond

IL-18 R beta (IL-1R7), also known as IL18RAP (Interleukin 18 Receptor Accessory Protein), is a member of the IL-1 family. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation.

Progrès de frontière

 
Progrès du développement médicamenteux
  • Nom anglais:

    Interleukin-18 receptor accessory protein

  • Catégorie:

  • Nombre de médicaments répertoriés:

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  • Nombre de médicaments cliniques:

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  • Étape de développement la plus élevée:

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