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Détails du produit
Synonyms
IL6R, CD126, IL-6R-1, IL-6RA, IL6RA, IL-6R-alpha, IL6RQ, gp80
Source
Mouse IL-6 R alpha Protein, Fc Tag (ILR-M5255) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Glu 357 (Accession # P22272-1).
Predicted N-terminus: Leu 20
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 63.9 kDa. The protein migrates as 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
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Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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Affichage des données
SDS-PAGE
Mouse IL-6 R alpha Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS
The purity of Mouse IL-6 R alpha Protein, Fc Tag (Cat. No. ILR-M5255) is more than 85% and the molecular weight of this protein is around 145-175 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Mouse IL-6, His Tag (Cat. No. IL6-M5245) at 5 μg/mL (100 μL/well) can bind Mouse IL-6 R alpha Protein, Fc Tag (Cat. No. ILR-M5255) with a linear range of 1-10 ng/mL (QC tested).
Protocol
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Introduction de fond
Progrès de frontière
Progrès du développement médicamenteux- Nom anglais：
Interleukin-6 receptor alpha subunit
- Catégorie：
- Nombre de médicaments répertoriés：
8 Détails
- Nombre de médicaments cliniques：
9 Détails
- Étape de développement la plus élevée：
Approved
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