Human LILRA5 / CD85f / ILT11 Protein, His Tag

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Cat. No. / Size
Price
Qty
LI5-H52H3-100ug
$410.00
LI5-H52H3-1mg
$2885.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    LILRA5, CD85f, ILT11, LIR9, LILRB7

  • Source

    Human LILRA5, His Tag (LI5-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 42 - Arg 268 (Accession # A6NI73-1).

    Predicted N-terminus: Gly 42

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  • Molecular Characterization

    LILRA5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 27.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    LILRA5 SDS-PAGE

    Human LILRA5, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

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Background

LIRs are immunoglobulin-like receptors that have activating and inhibitory functions in leukocytes. Leukocyte immunoglobulin-like receptor A5 (LILRA5) belongs to a family of receptors known to regulate leukocyte activation. LILRA5, expressed as a membrane-bound receptor and as a secreted molecule. The transmembrane LILRA5 contain a short cytoplasmic domain and a charged arginine residue within the transmembrane region that is likely to mediate its association with another coreceptor. LILRA5 is mostly expressed in myeloid cells, including monocytes and neutrophils.

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