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Détails du produit
Synonyms
CD85J, LILRB1, CD85, ILT2, LIR1, MIR7
Source
Human LILRB1 (23-431) Protein, His Tag (CDJ-H52H6) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Thr 431 (Accession # Q8NHL6-1).
Predicted N-terminus: Ala 23
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 46.5 kDa. The protein migrates as 58-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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Affichage des données
SDS-PAGE
Human LILRB1 (23-431) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS
The purity of Human LILRB1 (23-431) Protein, His Tag (Cat. No. CDJ-H52H6) is more than 95% and the molecular weight of this protein is around 45-55 kDa verified by SEC-MALS.
Report
Bioactivity-SPR
Biotinylated Human HLA-G&B2M&Peptide (RIIPRHLQL) Complex Protein (Cat. No. HLM-H82E4) captured on Biotin CAP-Series S Sensor Chip can bind Human LILRB1 (23-431) Protein, His Tag (Cat. No. CDJ-H52H6) with an affinity constant of 6.31 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Protocol
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Introduction de fond
Progrès de frontière
Progrès du développement médicamenteux- Nom anglais：
Leukocyte immunoglobulin-like receptor B1
- Catégorie：
- Nombre de médicaments répertoriés：
0 Détails
- Nombre de médicaments cliniques：
7 Détails
- Étape de développement la plus élevée：
Phase 2 Clinical
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