Cat. No. / Size
Price
Availability
Qty
MA3-H5243-20ug
$300.00
MA3-H5243-100ug
$1,120.00
MA3-H5243-500ug
$3,850.00
Sub-Total:
$ 0
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分子别名(Synonym)

MASP3, MASP1, CRARF1, RaRF

表达区间及表达系统(Source)

Human MASP3, His Tag (MA3-H5243) is expressed from human 293 cells (HEK293). It contains AA Gly 298 - Val 721 (Accession # P48740-2).

Predicted N-terminus: His

蛋白结构(Molecular Characterization)

Online(Gly 298 - Val 721) P48740-2

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 48.7 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Delivered as bulk protein in a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, pH8.0 with trehalose as protectant.

Contact us for customized product form or formulation.

运输(Shipping)

This product is supplied as sterile liquid solution and shipped frozen with dry ice.

存储(Storage)

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. The product MUST be stored at -70°C or lower upon receipt;
  2. -70°C for 3 months under sterile conditions.

Background

MASP3 is a member of the MASP family. The MASP family proteins were first discovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associated serine proteases, but later, they were found to interact with ficolins, and later still, collectin-10 and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includes non-enzymatic factors (MAp19, MAp44). In this review, the association-specific factors of the lectin pathway with haematologic malignancies and related infections are discussed.