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Mouse NSE Protein, His Tag (MALS verified)

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Numéro de produit/spécification
Prix
Qté
NSE-M5147-25ug
$145.00
NSE-M5147-100ug
$360.00
NSE-M5147-500ug
$1080.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Synonyms

    Neuron-specific enolase, gamma-enolase

  • Source

    Mouse NSE, His Tag (NSE-M5147) is expressed from E. coli cells. It contains AA Met 1 - Met 431 (Accession # Q545V3-1).

    Predicted N-terminus: Met

    Request for sequence
  • Molecular Characterization

    NSE Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 49.3 kDa. The protein migrates as 47-50 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 0.5 M Arginine, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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  • SDS-PAGE

    NSE SDS-PAGE

    Mouse NSE, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    NSE SEC-MALS

    The purity of Mouse NSE, His Tag (Cat. No. NSE-M5147) is more than 95% and the molecular weight of this protein is around 100-115 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     NSE ELISA

    Immobilized Mouse NSE, His Tag (Cat. No. NSE-M5147) at 1 μg/mL (100 μL/well) can bind Anti-NSE Antibody with a linear range of 0.004-0.125 μg/mL (QC tested).

    Protocol

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Introduction de fond

Neuron-specific enolase (NSE) is known to be a cell specific isoenzyme of the glycolytic enzyme enolase. It is also known as
gamma-enolase or nolase 2 (ENO2). It has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. NSE is a highly specific marker for neurons and peripheral neuroendocrine cells. In clinical, NSE could be used as a biomarker for neuronal injury.

Progrès de frontière

 
Progrès du développement médicamenteux
  • Nom anglais:

    Gamma-enolase

  • Catégorie:

  • Nombre de médicaments répertoriés:

    0 Détails

  • Nombre de médicaments cliniques:

    0 Détails

  • Étape de développement la plus élevée:

    Preclinical

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