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Mouse Prolactin / PRL Protein, His Tag (MALS & SPR verified)

AIDD‑Ready
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PRN-M52H3-100ug
$310.00
In Stock - Delivery in 1-2 business days
PRN-M52H3-1mg (500ug X 2)
$2,245.00
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PRN-M52H3
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

PRL, Prolactin

Source

Mouse Prolactin Protein, His Tag (PRN-M52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 30 - Cys 226 (Accession # P06879).

Predicted N-terminus: Leu 30

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 24.3 kDa. The protein migrates as 23-25 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

Prolactin is a versatile hormone primarily secreted by the anterior pituitary gland. Its most recognized function is stimulating milk production (lactogenesis) in mammals following childbirth. Beyond this, it influences a wide array of physiological processes, including immune regulation, metabolism, and reproductive functions in both sexes, contributing to behaviors like parental care. Its secretion is predominantly under inhibitory control by dopamine from the hypothalamus. Other factors, such as thyrotropin-releasing hormone (TRH), estrogen, and suckling, can stimulate its release. Abnormal prolactin levels can lead to clinical conditions, such as hyperprolactinemia, which may cause infertility and galactorrhea.