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Human SLC1A5 Full Length Protein, His,Flag Tag (Nanodisc-pro)

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Numéro de produit/spécification
Prix
Qté
SL5-H52D3-20ug
$750.00
SL5-H52D3-100ug
$1500.00
SL5-H52D3-500ug
$4800.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Application

    1. Cell based assay (FACS or functional assay)
    2. Affinity testing (SPR / BLI)
    3. Screening (ELISA)
  • Synonyms

    ASCT2, M7V1, RDR, RDRC, ATB(0), AAAT, ASCT2M7VS1, M7V1ATBO, R16, RD114, RDRCFLJ31068

  • Source

    Nanodisc-pro Human SLC1A5 Full Length Protein, His,Flag Tag (SL5-H52D3) is expressed from human 293 cells (HEK293). It contains AA Val 2 - Met 541 (Accession # Q15758-1).

    Request for sequence
  • Molecular Characterization

    SLC1A5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus and a Flag tag at the C-terminus.

    *The isotype control of empty/mock nanodisc (Cat. No. APO-H5143) is sold separately and not included in protein, you can follow the link for product information.

    1. Structure

      Nanodisc-pro membrane protein is wrapped by a piece of cell membrane and scaffold, the info of scaffold can be found in above red text "isotope type control...".

    2. Synthesis Process

      Nanodisc-pro membrane protein extraction is a gentle, non-disruptive process that directly isolates full-length transmembrane proteins together with their surrounding native phospholipids from cellular membranes, without breaking or disturbing the original membrane structure. This preserves the membrane protein's natural conformational landscape and native lipid environment, yielding stable nanodisc that retain cellular phospholipids, with fully preserved biological activity—making them ideal for cell-based assays such as FACS and binding assays in antibody discovery and screening (ELISA), etc.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 20 mM HEPES, 150 mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping and Storage

    This product is supplied and shipped on dry ice.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Affichage des données

  • Bioactivity-ELISA

     SLC1A5 ELISA

    Immobilized Human SLC1A5 Full Length Protein, His,Flag Tag (Cat. No. SL5-H52D3) at 5 μg/mL (100 μL/well) can bind ASCT2 Rabbit Monoclonal Antibody with a linear range of 0.002-0.125 μg/mL (QC tested).

    Protocol

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  • E***a2026-04-29
    J'aime
    I was using this item as for POC project and it worked really well in our assay. I appreciate that more nanodisc proteins are becoming available commercially. Thanks so much!

Introduction de fond

SLC1A5, a neutral amino acid transporter mediating glutamine uptake essential for rapidly proliferating cancer cells. It fuels the TCA cycle, nucleotide biosynthesis, and mTORC1 signaling. SLC1A5 is a metabolic oncology target; inhibitors aim to starve tumors of glutamine and induce metabolic crisis and growth arrest.

Progrès de frontière

 
Progrès du développement médicamenteux
  • Nom anglais:

    Neutral amino acid transporter B(0)

  • Catégorie:

  • Nombre de médicaments répertoriés:

    0 Détails

  • Nombre de médicaments cliniques:

    0 Détails

  • Étape de développement la plus élevée:

    Preclinical

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