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Product Details
Synonyms
DDPAC, FTDP-17, MAPT, MSTD, MTBT1, Tau, PHF-tau, TAU
Source
Human Tau-441 GSK-3beta-phosphorylated Protein, Tag Free (TAU-H511e) is expressed from E. coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8).
Predicted N-terminus: Met 1
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries no "tag".
The protein has a calculated MW of 45.8 kDa. The protein migrates as 40 kDa, 50 kDa and 55-63 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity
>90% as determined by SDS-PAGE.
Formulation
Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.
Contact us for customized product form or formulation.
Shipping and Storage
This product is supplied and shipped on dry ice.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- The product MUST be stored at -70°C or lower upon receipt;
- -70°C for 3 months under sterile conditions.
ACRO Quality Management System
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Performance Data
SDS-PAGE
Human Tau-441 GSK-3beta-phosphorylated Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
Bioactivity-ELISA
Immobilized Human Tau-441 GSK-3beta-phosphorylated Protein, Tag Free (Cat. No. TAU-H511e) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Phospho-Tau (Thr181) Antibody, Mouse IgG with a linear range of 0.0005-0.125 μg/mL (QC tested).
Protocol
Immobilized Human Tau-441 GSK-3beta-phosphorylated Protein, Tag Free (Cat. No. TAU-H511e) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Tau (phospho T217) Antibody, Rabbit IgG with a linear range of 0.0005-0.5 μg/mL (Routinely tested).
Protocol
Immobilized Human Tau-441 GSK-3beta-phosphorylated Protein, Tag Free (Cat. No. TAU-H511e) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Tau (phospho T231) Antibody, Rabbit IgG with a linear range of 0.0005-0.125 μg/mL (Routinely tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
Microtubule-associated protein tau
- Category：
- Approved Drugs：
1 Details
- Drugs in Clinical Trials：
46 Details
- Highest Development Stage：
Approved
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