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Page d'accueilToutes les moléculesALPP
ALPP
ALPP Informations sur la molécule
| Nom anglais | Alkaline phosphatase, placental type | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 2 | Alias de la cible | Alkaline phosphatase Regan isozyme，Placental alkaline phosphatase 1，PLAP-1 |
| Phase de R&D la plus avancée | Phase 2 Clinical | ||
| Nom anglais | Alkaline phosphatase, placental type |
| Alias de la cible | Alkaline phosphatase Regan isozyme，Placental alkaline phosphatase 1，PLAP-1 |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 2 |
| Phase de R&D la plus avancée | Phase 2 Clinical |
ALPP Liste de produits
- Attribut
Protein (4)Antibody (1)
- Bibliothèque de produits
En ligne (5)
- Espèces
Cynomolgus (1)Human (2)Mouse (1)Rat (1)
- Étiquette
His Tag (3)- (1)His Tag & Avi Tag (1)
- Marqueur
Unconjugated (4)Biotin-labeled (1)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
HOT ALP-H52H3 |  Human | HEK293 | Human ALPP Protein, His Tag (active enzyme, MALS verified) |  |  |  |  Ajouter au panier |
HOT ALP-H82E3 | Human | HEK293 | Biotinylated Human ALPP Protein, His,Avitag™ (active enzyme, MALS verified) |  | | | Ajouter au panier |
HOT ALP-R52H4 |  Rat | HEK293 | Rat ALPP Protein, His Tag (active enzyme) |  | | | Ajouter au panier |
 Mouse | - | Recombinant Monoclonal Anti-ALPP Antibody, Mouse (1B10) | Ajouter au panier | ||||
 Cynomolgus | HEK293 | Cynomolgus ALPP Protein, His Tag (active enzyme) |  | | | Ajouter au panier |
Quantité totale5
- 1
ALPPContexte de la molécule
Placental alkaline phosphatase (ALPP) is a membrane-bound enzyme normally restricted to placental tissue. However, it is aberrantly overexpressed in various solid tumors, including ovarian, testicular, and cervical cancers, making it a highly specific tumor biomarker. High-affinity anti-ALPP antibodies are essential for early clinical cancer diagnostics (IHC/serum screening) and the development of targeted therapies like antibody-drug conjugates (ADCs) and CAR-T cells.
ALPPAlias de la molécule
PLAP
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| Retroviral vector-transduced autologous T cells to express anti-ALPP CARs (TCRCure Biopharma Corporation) | Phase 2 Clinical | Xinqiao Hospital, Army Medical University | Endometrial Neoplasms; Ovarian Neoplasms; Solid tumours | Details | |
| anti-ALPP CAR T-cell therapy (TCRCure Biopharma) | TC-A101 | Phase 1 Clinical | Tcrcure Biopharma Ltd | Solid tumours | Details |
- Liste de produits
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