Amphiregulin

Amphiregulin Informations sur la molécule

Nom anglais	Amphiregulin	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2	Alias de la cible	AREGB，Colorectum cell-derived growth factor，AR，Schwannoma-Derived Growth Factor，Amphiregulin B，CRDGF，SDGF，SDGF GN
Phase de R&D la plus avancée	Phase 1 Clinical

Nom anglais	Amphiregulin
Alias de la cible	AREGB，Colorectum cell-derived growth factor，AR，Schwannoma-Derived Growth Factor，Amphiregulin B，CRDGF，SDGF，SDGF GN
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2
Phase de R&D la plus avancée	Phase 1 Clinical

Amphiregulin Liste de produits

Attribut
Protein (2)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
His Tag & Avi Tag (2)
Marqueur
Biotin-labeled (2)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
AMN-H82Q3	Human	HEK293	Biotinylated Human Amphiregulin Protein, His,Avitag™				Ajouter au panier
AMN-H82Q4	Human	HEK293	Biotinylated Human Amphiregulin Protein, His,Avitag™ (HPLC verified)				Ajouter au panier

Quantité totale2

Demande de produit

AmphiregulinContexte de la molécule

Amphiregulin (AREG), which acts as one of the ligands for epidermal receptor growth factor receptor (EGFR), plays a crucial role in tissue repair, inflammation, and immunity. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]

AmphiregulinAlias de la molécule

AR, AREGB, CRDGF, SDGF

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
SRN-001	SRN-001	Phase 1 Clinical	siRNAgen Therapeutics Inc	Metabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Pulmonary Fibrosis; Chronic Kidney Disease-Mineral and Bone Disorder	Details
PMG-1015	PMG-1015	Phase 1 Clinical	Pulmongene Ltd	Idiopathic Pulmonary Fibrosis	Details