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Angiopoietin-like 4

Angiopoietin-like 4 Informations sur la molécule

Nom anglaisAngiopoietin-related protein 4Nombre de médicaments commercialisés0
Nombre de médicaments cliniques3Alias de la cibleAngiopoietin-like protein 4,Hepatic fibrinogen/angiopoietin-related protein,HFARP,ARP4,PGAR,PP1158,PSEC0166,UNQ171/PRO197,Angiopoietin Like 4,Hepatic Fibrinogen/Angiopoietin-Related Protein,Angiopoietin-Related Protein 4,Pp1158,FIAF,NL2,Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Induced Angiopoietin-Related Protein,Hepatic Angiopoietin-Related Protein,PPARG Angiopoietin Related Protein,Fasting-Induced Adipose Factor,Angiopoietin-Like Protein 4,Angiopoietin-Like 4,UNQ171,TGQTL,HARP
Phase de R&D la plus avancéePhase 2 Clinical
Nom anglaisAngiopoietin-related protein 4
Alias de la cibleAngiopoietin-like protein 4,Hepatic fibrinogen/angiopoietin-related protein,HFARP,ARP4,PGAR,PP1158,PSEC0166,UNQ171/PRO197,Angiopoietin Like 4,Hepatic Fibrinogen/Angiopoietin-Related Protein,Angiopoietin-Related Protein 4,Pp1158,FIAF,NL2,Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Induced Angiopoietin-Related Protein,Hepatic Angiopoietin-Related Protein,PPARG Angiopoietin Related Protein,Fasting-Induced Adipose Factor,Angiopoietin-Like Protein 4,Angiopoietin-Like 4,UNQ171,TGQTL,HARP
Nombre de médicaments commercialisés0
Nombre de médicaments cliniques3
Phase de R&D la plus avancéePhase 2 Clinical

Angiopoietin-like 4 Liste de produits

  • Attribut

    Protein (1)

  • Bibliothèque de produits

    En ligne (1)

  • Espèces

    Human (1)

  • Étiquette

    His Tag (1)

  • Marqueur

    Unconjugated (1)

Numéro de produitEspècesSystème d'expressionDescription du produitStructure protéiquePuretéCaractéristiquesPré-commande/Commande
AN4-H5243
Human
HEK293
Human Angiopoietin-like 4 / ANGPTL4 (166-406) Protein, His Tag
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Quantité totale1
  • 1

Angiopoietin-like 4Contexte de la molécule

Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.

Angiopoietin-like 4Alias de la molécule

ANGPTL4,ARP4,FIAF,HFARP,PGAR,pp1158,Angiopoietin like 4

Informations sur les médicaments cliniques

Nom anglaisCode de recherchePhase de R&DEntrepriseIndicationEssai clinique
MAR001MAR001; MAR-001Phase 2 ClinicalMareas Therapeutic Services IncHypertriglyceridemia
Details
LipisensePhase 1 ClinicalLipigon Pharmaceuticals AB, Secarna Pharmaceuticals GmbH & Co KGHypertriglyceridemia
Details
A24110HeA24110He; A-24110-HePhase 1 ClinicalLipigon Pharmaceuticals ABHyperlipidemias; Hypertriglyceridemia
Details
  • Informations sur la molécule
  • Liste de produits
  • Informations sur les médicaments cliniques