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Arginase 1

Arginase 1 Overview

English Name	Arginase-1	Approved Drugs	0
Drugs in Clinical Trials	2	Target Synonym	EC:3.5.3.1，Liver-type arginase，Type I arginase，ARG1，Arginase 1，Arginase， Liver，Arginase-1，EC 3.5.3.1
Highest Development Stage	Phase 2 Clinical

English Name	Arginase-1
Target Synonym	EC:3.5.3.1，Liver-type arginase，Type I arginase，ARG1，Arginase 1，Arginase， Liver，Arginase-1，EC 3.5.3.1
Approved Drugs	0
Drugs in Clinical Trials	2
Highest Development Stage	Phase 2 Clinical

Arginase 1 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
AR1-H5228	Human	HEK293	Human Arginase 1 / ARG1 Protein, His Tag

Total: 1

Arginase 1 Background

Arginase-1 (ARG1) is also known as Liver-type arginase, Type I arginase, which belongs to the arginase family. Arginase-1 / ARG1 is a manganese-containing enzyme. The reaction catalyzed by this enzyme is: arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle. Defects in Arginase-1 / ARG1 are the cause of argininemia (ARGIN).

Arginase 1 Synonyms

ARG1,Arginase-1

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Numidargistat	INCB-01158; CB-1158	Phase 2 Clinical	Calithera Biosciences Inc	Biliary Tract Neoplasms; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Multiple Myeloma; Neoplasm Metastasis; Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Urinary Bladder Neoplasms	Details
OATD-02	OAT-1746; OATD-02; EX-A8043; HY-155108	Phase 1 Clinical	OncoArendi Therapeutics Inc	Carcinoma, Renal Cell; Colorectal Neoplasms; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms	Details

Product Reviews

1***32019-10-11
1People Like
Human Arginase 1 / ARG1 Protein, His Tag
Enzyme activity is very high, basically there is no different from products of thermo and RD, but with a better price. The most impressive thing is that there is almost no difference on bioactivity among each batch, and the quality control is excellent!
1***22019-09-27
1People Like
Human Arginase 1 / ARG1 Protein, His Tag
I bought another product for our laboratory before. This time I needed to buy Human Arginase 1 / ARG1 Protein, His Tag. All my senior coworkers recommended me to buy from ACRO, so I bought one to try. Indeed, as expected, it was great. Product quality and customer service was also good.