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Arginase 1

Arginase 1

Arginase 1 Overview

Molecule Name
Arginase-1
Synonyms
ARG1,Arginase-1
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
EC:3.5.3.1，Liver-type arginase，Type I arginase，ARG1，Arginase 1，Arginase， Liver，Arginase-1，EC 3.5.3.1
Background
Arginase-1 (ARG1) is also known as Liver-type arginase, Type I arginase, which belongs to the arginase family. Arginase-1 / ARG1 is a manganese-containing enzyme. The reaction catalyzed by this enzyme is: arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle. Defects in Arginase-1 / ARG1 are the cause of argininemia (ARGIN).

Arginase 1 Product List

Species
  • Human（1）
Tag
  • His Tag（1）
Host
  • HEK293（1）
Conjugate
  • Unconjugated（1）
Grade
  • RUO（1）
Low Endotoxin
  • No（1）
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&Price
Arginase 1
AR1-H5228
Human Arginase 1 / ARG1 Protein, His Tag
Human
HEK293
SDS-PAGE

$360.00

50ug
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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
NumidargistatINCB-01158; CB-1158Phase 2 ClinicalCalithera Biosciences Inc
Biliary Tract Neoplasms; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Multiple Myeloma; Neoplasm Metastasis; Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Urinary Bladder Neoplasms
Details
OATD-02OAT-1746; OATD-02; EX-A8043; HY-155108Phase 1 ClinicalOncoArendi Therapeutics Inc
Carcinoma, Renal Cell; Colorectal Neoplasms; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms
Details
Customer Reviews
  • 1***32019-10-11
    Human Arginase 1 / ARG1 Protein, His Tag
    Enzyme activity is very high, basically there is no different from products of thermo and RD, but with a better price. The most impressive thing is that there is almost no difference on bioactivity among each batch, and the quality control is excellent!
  • 1***22019-09-27
    Human Arginase 1 / ARG1 Protein, His Tag
    I bought another product for our laboratory before. This time I needed to buy Human Arginase 1 / ARG1 Protein, His Tag. All my senior coworkers recommended me to buy from ACRO, so I bought one to try. Indeed, as expected, it was great. Product quality and customer service was also good.