B7-H7

B7-H7 Informations sur la molécule

Nom anglais	HERV-H LTR-associating protein 2	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	3	Alias de la cible	Human endogenous retrovirus-H long terminal repeat-associating protein 2，B7-H7，B7H7
Phase de R&D la plus avancée	Phase 1 Clinical

Nom anglais	HERV-H LTR-associating protein 2
Alias de la cible	Human endogenous retrovirus-H long terminal repeat-associating protein 2，B7-H7，B7H7
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	3
Phase de R&D la plus avancée	Phase 1 Clinical

B7-H7 Liste de produits

Attribut
Protein (7)
Bibliothèque de produits
En ligne (7)
Espèces
Human (5)Cynomolgus (2)
Étiquette
Fc Tag & Avi Tag (2)Fc Tag (1)His Tag (2)His Tag & Avi Tag (2)
Marqueur
Biotin-labeled (4)Unconjugated (3)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT B77-H5257	Human	HEK293	Human B7-H7 / HHLA2 Protein, Fc Tag (MALS verified)	Ajouter au panier
HOT B77-H52H6	Human	HEK293	Human B7-H7 / HHLA2 Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
HOT B77-H82E3	Human	HEK293	Biotinylated Human B7-H7 / HHLA2 Protein, His,Avitag™ (MALS verified)	Ajouter au panier
HOT B77-C52H3	Cynomolgus	HEK293	Cynomolgus B7-H7 / HHLA2 Protein, His Tag (MALS verified)	Ajouter au panier
B77-H82F3	Human	HEK293	Biotinylated Human B7-H7 / HHLA2 Protein, Fc,Avitag™ (MALS verified)	Ajouter au panier
B77-H82F5	Human	HEK293	Biotinylated Human B7-H7 / HHLA2 Protein, Fc,Avitag™ (MALS verified)	Ajouter au panier
B77-C82E9	Cynomolgus	HEK293	Biotinylated Cynomolgus B7-H7 / HHLA2 Protein, His,Avitag™	Ajouter au panier

Quantité totale7

B7-H7Contexte de la molécule

B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.

B7-H7Alias de la molécule

B7-H7,HHLA2,B7 Homolog 7

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
HBM-1020	R-1020; HBM-1020	Phase 1 Clinical	Harbour Biomed	Solid tumours	Details
NPX-372	NPX372; NPX-372	Phase 1 Clinical	NextPoint Therapeutics Inc	Solid tumours	Details
NPX-887	NPX887; NPX-887	Phase 1 Clinical	NextPoint Therapeutics Inc	Neoplasms; Solid tumours	Details

Avis sur les produits

A***r2025-11-15
0Mettre un like
Human B7-H7 / HHLA2 Protein, His Tag, low endotoxin (MALS verified)
I have been using ACRO Biosystems products since 2021, especially DLL4 Fc proteins (DL4-H5259), refer to our published article: https://pubmed.ncbi.nlm.nih.gov/37795096/, where we have used Acro-products and obtained excellent results. Recently, I ordered Human B7-H7 / HHLA2 Protein, His Tag (B77-H52H6-100 µg) for my ELISA assay, and it performed exceptionally well-as expected (Unpublished data). I am very satisfied with the consistent quality and reliability of ACRO’s products. Thanks, Ankit Tanwar Staff Scientist AECOM, NY