CA125

CA125 Informations sur la molécule

Nom anglais	Mucin-16	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	11	Alias de la cible	Mucin-16 Short Isoform，Mucin-16 Long Isoform，Ovarian carcinoma antigen CA125，Ovarian cancer-related tumor marker CA125，MUC16，MUC-16，CA-125，Mucin 16， Cell Surface Associated，CA125，CA125 Ovarian Cancer Antigen，Mucin-16，CA-125 Antigen，FLJ14303
Phase de R&D la plus avancée	Phase 3 Clinical

Nom anglais	Mucin-16
Alias de la cible	Mucin-16 Short Isoform，Mucin-16 Long Isoform，Ovarian carcinoma antigen CA125，Ovarian cancer-related tumor marker CA125，MUC16，MUC-16，CA-125，Mucin 16， Cell Surface Associated，CA125，CA125 Ovarian Cancer Antigen，Mucin-16，CA-125 Antigen，FLJ14303
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	11
Phase de R&D la plus avancée	Phase 3 Clinical

CA125 Liste de produits

Attribut
Protein (8)
Bibliothèque de produits
En ligne (8)
Espèces
Human (3)Cynomolgus (2)Mouse (1)Rabbit (1)Rat (1)
Étiquette
Fc Tag & Avi Tag (2)His Tag (5)His Tag & Avi Tag (1)
Marqueur
Biotin-labeled (3)Unconjugated (5)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT CA5-H52H6	Human	HEK293	Human CA125 / MUC16 (13810-14451) Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
HOT CA5-H82F4	Human	HEK293	Biotinylated Human CA125 / MUC16 Protein, Fc,Avitag™	Ajouter au panier
HOT CA5-H82F8	Human	HEK293	Biotinylated Human CA125 / MUC16 (13810-14451) Protein, Fc,Avitag™	Ajouter au panier
CA5-M52H6	Mouse	HEK293	Mouse CA125 / MUC16 Protein, His Tag (MALS verified)	Ajouter au panier
CA5-C52H8	Cynomolgus	HEK293	Cynomolgus CA125 / MUC16 Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
CA5-C82E9	Cynomolgus	HEK293	Biotinylated Cynomolgus CA125 / MUC16 Protein, His,Avitag™ (MALS verified)	Ajouter au panier
CA5-R52H4	Rabbit	HEK293	Rabbit CA125 / MUC16 Protein, His Tag	Ajouter au panier
CA5-R52H5	Rat	HEK293	Rat CA125 Protein, His Tag (MALS verified)	Ajouter au panier

Quantité totale8

Demande de produit

CA125Contexte de la molécule

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

CA125Alias de la molécule

CA125,CA-125,CA125MUC-16,FLJ14303,MUC16,mucin 16,mucin-16

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Oregovomab	B43.13	Phase 3 Clinical	Paladin Pharma	Abdominal Neoplasms; Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms	Details
EB-NK-FM (FRalpha/MUC16)	EB-NK-FM	Phase 2 Clinical	Beijing Biotech	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	Details
EB-NK-MM (MSLN/MUC16)	EB-NK-MM	Phase 2 Clinical	Beijing Biotech	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	Details
LBL-033	LBL-033	Phase 2 Clinical	Nanjing Leadsbiolabs Co Ltd	Neoplasms	Details
REGN-5668	REGN-5668	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Endometrial Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms	Details
Ubamatamab	REGN-4018	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fallopian Tube Neoplasms; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms	Details
PRGN-3005	PRGN-3005	Phase 1 Clinical	Precigen Inc	Esophageal Neoplasms; Fallopian Tube Neoplasms; Lymphoma, Non-Hodgkin; Ovarian Neoplasms; Peritoneal Neoplasms; Sarcoma; Uterine Cervical Neoplasms	Details
GB-5267	GB-5267	Phase 1 Clinical	Generate Biomedicines Inc	Ovarian Neoplasms	Details
HWK-016	HWK-016	Phase 1 Clinical	Wuxi Biologics Co Ltd	Endometrial Neoplasms; Ovarian Neoplasms; Uterine Cervical Neoplasms	Details
JCAR-020	JCAR-020	Phase 1 Clinical	Eureka Therapeutics Inc, Juno Therapeutics Inc, Memorial Sloan Kettering Cancer Center	Solid tumours	Details
Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy(Regeneron Pharmaceutical)	27T-51; 27T51	Phase 1 Clinical	Regeneron Pharmaceuticals Inc	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	Details

Avis sur les produits

E***e2025-08-07
0Mettre un like
Human CA125 / MUC16 (13810-14451) Protein, His Tag, low endotoxin (MALS verified)
We used Acro Biosystems' recombinant Human CA125 / MUC16 protein (Catalog #CA5-H52H6) as a target antigen for antibody screening and downstream validation. The protein was employed in both ELISA and FACS assays. In ELISA, we observed strong, dose-dependent binding with minimal background, which enabled clear differentiation of candidate clones. For FACS, we used the protein to confirm surface staining specificity on engineered cell lines, and the results were consistent and reproducible. I was particularly impressed with the proteins high purity.