CCL2

CCL2 Informations sur la molécule

Nom anglais	C-C motif chemokine 2	Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	3	Alias de la cible	MCP1，HC11，Monocyte chemotactic protein 1，Monocyte chemoattractant protein 1，CCL2，C-C Motif Chemokine Ligand 2，Monocyte Chemotactic And Activating Factor，Monocyte Secretory Protein JE，Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je)，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 2，Monocyte Chemoattractant Protein-1，Chemokine (C-C Motif) Ligand 2，Small-Inducible Cytokine A2，SCYA2，MCP-1，MCAF，Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je，C-C Motif Chemokine 2，HSMCR30，GDCF-2，SMC-CF，Chemokine CCL2，MGC9434
Phase de R&D la plus avancée	Approved

Nom anglais	C-C motif chemokine 2
Alias de la cible	MCP1，HC11，Monocyte chemotactic protein 1，Monocyte chemoattractant protein 1，CCL2，C-C Motif Chemokine Ligand 2，Monocyte Chemotactic And Activating Factor，Monocyte Secretory Protein JE，Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je)，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 2，Monocyte Chemoattractant Protein-1，Chemokine (C-C Motif) Ligand 2，Small-Inducible Cytokine A2，SCYA2，MCP-1，MCAF，Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je，C-C Motif Chemokine 2，HSMCR30，GDCF-2，SMC-CF，Chemokine CCL2，MGC9434
Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	3
Phase de R&D la plus avancée	Approved

CCL2 Liste de produits

Attribut
Protein (1)Kits (1)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
Fc Tag (1)- (1)
Marqueur
Unconjugated (1)- (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
CC2-H5255	Human	HEK293	Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified)				Ajouter au panier
CEA-B036	Human	-	Human MCP-1 / CCL2 ELISA Kit				Ajouter au panier

Quantité totale2

CCL2Contexte de la molécule

Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. CCL2, a member of the CC subfamily, is characterized by two adjacent cysteine residues. CCL2 displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

CCL2Alias de la molécule

CCL2,C-C motif chemokine 2,MCP-1,MCAF

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
AFX-5931	AFX-5931	Phase 2 Clinical	Afecta Pharmaceuticals Inc	Eczema	Details
MW-151	MW01-9-034WH; MW-151; MW01-2-151SRM	Phase 1 Clinical	University Of Kentucky	Drug-Related Side Effects and Adverse Reactions; Poisoning	Details
64CU-DOTA-ECL1i		Phase 1 Clinical	Washington University School Of Medicine	Arteriosclerosis; Carotid Artery Diseases; Heart Diseases	Details