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CCL24

CCL24 Informations sur la molécule

Nom anglaisChemokine (C-C Motif) Ligand 24Nombre de médicaments commercialisés0
Nombre de médicaments cliniques1Alias de la cibleSmall Inducible Cytokine Subfamily A (Cys-Cys), Member 24,Chemokine (C-C Motif) Ligand 24,Small-Inducible Cytokine A24,MPIF-2,Ckb-6,Chemokine CCL24,MPIF2,SCYA24,Eotaxin-2,CK-beta-6,Myeloid progenitor inhibitory factor 2,C-C motif chemokine 24,CCL24,C-C Motif Chemokine Ligand 24,Eosinophil Chemotactic Protein 2
Phase de R&D la plus avancéePhase 2 Clinical
Nom anglaisChemokine (C-C Motif) Ligand 24
Alias de la cibleSmall Inducible Cytokine Subfamily A (Cys-Cys), Member 24,Chemokine (C-C Motif) Ligand 24,Small-Inducible Cytokine A24,MPIF-2,Ckb-6,Chemokine CCL24,MPIF2,SCYA24,Eotaxin-2,CK-beta-6,Myeloid progenitor inhibitory factor 2,C-C motif chemokine 24,CCL24,C-C Motif Chemokine Ligand 24,Eosinophil Chemotactic Protein 2
Nombre de médicaments commercialisés0
Nombre de médicaments cliniques1
Phase de R&D la plus avancéePhase 2 Clinical

CCL24 Liste de produits

  • Attribut

    Protein (1)

  • Bibliothèque de produits

    En ligne (1)

  • Espèces

    Human (1)

  • Étiquette

    His Tag (1)

  • Marqueur

    Unconjugated (1)

Numéro de produitEspècesSystème d'expressionDescription du produitStructure protéiquePuretéCaractéristiquesPré-commande/Commande
Human
HEK293
Human CCL24/Eotaxin-2 Protein, His Tag (HPLC verified)
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Quantité totale1
  • 1

CCL24Contexte de la molécule

C-C motif chemokine ligand 24 (CCL24), also known as eotaxin2, belongs to CC chemokines like MCP-1, and it mainly chemoattracts eosinophils. CCL24 can promote the separation of eosinophils from endothelial cells and then combine with its sole ligand to promote eosinophils to enter the tissue. CCL24 was not originally found in eosinophils but was first isolated from monocytes. Latest, it was found that the expression of CCL24 in the bronchial epithelial cells of asthma patients increased. CCL24 promotes immune cell trafficking and activation as well as profibrotic activities through the CCR3 receptor (C-C chemokine receptor type 3). Both CCL24 and CCR3 is involved in lung and skin inflammation and fibrosis.

CCL24Alias de la molécule

C-C motif chemokine 24,CK-beta-6,Eosinophil chemotactic protein 2,Myeloid progenitor inhibitory factor 2,Small-inducible cytokine A24,Eotaxin-2,MPIF-2,SCYA24,MPIF2

Informations sur les médicaments cliniques

Nom anglaisCode de recherchePhase de R&DEntrepriseIndicationEssai clinique
NebokitugCM-101Phase 2 ClinicalChemomab Therapeutics LtdCholangitis, Sclerosing; Metabolic Dysfunction-Associated Steatotic Liver Disease; Scleroderma, Systemic
Details
  • Informations sur la molécule
  • Liste de produits
  • Informations sur les médicaments cliniques