CD133

CD133 Informations sur la molécule

Nom anglais	CD133	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2	Alias de la cible	Antigen AC133，Prominin-1，PROM1，Prominin 1，Prominin-Like Protein 1，PROML1，Stargardt Disease 4 (Autosomal Dominant)，Hematopoietic Stem Cell Antigen，Macular Dystrophy， Retinal 2，Prominin (Mouse)-Like 1，CD133 Antigen，HProminin，MSTP061，CORD12，AC133，CD133，MCDR2，STGD4，RP41，AC133 Antigen
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	CD133
Alias de la cible	Antigen AC133，Prominin-1，PROM1，Prominin 1，Prominin-Like Protein 1，PROML1，Stargardt Disease 4 (Autosomal Dominant)，Hematopoietic Stem Cell Antigen，Macular Dystrophy， Retinal 2，Prominin (Mouse)-Like 1，CD133 Antigen，HProminin，MSTP061，CORD12，AC133，CD133，MCDR2，STGD4，RP41，AC133 Antigen
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2
Phase de R&D la plus avancée	Phase 2 Clinical

CD133 Liste de produits

Attribut
Protein (7)Cell (1)
Bibliothèque de produits
En ligne (8)
Espèces
Human (7)Cynomolgus (1)
Étiquette
His Tag (3)- (3)His Tag & Avi Tag (1)His Tag & Flag Tag (1)
Marqueur
Unconjugated (4)Biotin-labeled (2)- (1)PE Labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT CD3-H52H1	Human	HEK293	Human CD133 Full Length Protein, His Tag (Nanodisc)	Ajouter au panier
HOT CD3-H52P3	Human	HEK293	Human CD133 Full Length Protein (VLP)	Ajouter au panier
HOT CD3-C82E3	Cynomolgus	HEK293	Biotinylated Cynomolgus CD133 Full Length Protein, His,Avitag™ (Detergent)	Ajouter au panier
CD3-H51D3	Human	E. coli	Human CD133 Full Length Protein, His,Flag Tag (Detergent)	Ajouter au panier
CD3-H52H4	Human	HEK293	Human CD133 Protein, His Tag (Detergent)	Ajouter au panier
CD3-H82D3	Human	HEK293	Biotinylated Human CD133 Full Length Protein, His,Flag Tag&Avitag™ (Detergent)	Ajouter au panier
CD3-HP2H8	Human	HEK293	PE-Labeled Human CD133 Protein, His Tag	Ajouter au panier
CHEK-ATP255	Human	HEK293	HEK293/Human CD133 Stable Cell Line	Ajouter au panier

Quantité totale8

CD133Contexte de la molécule

Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

CD133Alias de la molécule

CD133,PROM1,PROML1,Prominin-1,AC133

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
P-134	P-134; P134	Phase 2 Clinical	Tianjin Tasly Pharmaceutical Co Ltd	Glioblastoma	Details
anti-CD133-CAR vector-transduced T cells		Phase 2 Clinical	Pla General Hospital	Brain Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Liver Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Details