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Page d'accueilToutes les moléculesCD2
CD2
CD2 Informations sur la molécule
| Nom anglais | T-cell surface antigen CD2 | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 3 | Alias de la cible | T11，T-Cell Surface Antigen CD2，LFA-2，CD2 Antigens，CD2，LFA-3 Receptor，CD2 Molecule，Rosette Receptor，SRBC，CD2 Antigen，CD2 Antigen (P50)， Sheep Red Blood Cell Receptor，T-Cell Surface Antigen T11/Leu-5，Lymphocyte-Function Antigen-2，Erythrocyte Receptor |
| Phase de R&D la plus avancée | Phase 2 Clinical | ||
| Nom anglais | T-cell surface antigen CD2 |
| Alias de la cible | T11，T-Cell Surface Antigen CD2，LFA-2，CD2 Antigens，CD2，LFA-3 Receptor，CD2 Molecule，Rosette Receptor，SRBC，CD2 Antigen，CD2 Antigen (P50)， Sheep Red Blood Cell Receptor，T-Cell Surface Antigen T11/Leu-5，Lymphocyte-Function Antigen-2，Erythrocyte Receptor |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 3 |
| Phase de R&D la plus avancée | Phase 2 Clinical |
CD2 Liste de produits
- Attribut
Protein (6)Antibody (6)
- Bibliothèque de produits
En ligne (12)
- Espèces
Human (6)Cynomolgus (2)Rabbit (1)Mouse (3)
- Étiquette
His Tag (3)Fc Tag (1)His Tag & Avi Tag (2)- (6)
- Marqueur
Unconjugated (7)Biotin-labeled (2)PE Labeled (1)APC Labeled (2)
Ajouter au panier
Quantité totale12
- 1
- 2
CD2Contexte de la molécule
T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.
CD2Alias de la molécule
CD2,SRBC,LFA-2,T11
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| Siplizumab | MEDI-507; TCD-601 | Phase 2 Clinical | Catholic University Of Louvain, Itb-Med Llc | Amyotrophic Lateral Sclerosis; Anemia, Sickle Cell; Cholangitis, Sclerosing; Diabetes Mellitus, Type 1; End Stage Liver Disease; Graft vs Host Disease; Hepatitis, Autoimmune; Hidradenitis Suppurativa; Kidney Diseases; Kidney Failure, Chronic; Leukemia; Liver Cirrhosis; Liver Diseases; Lymphoma; Lymphoma, Extranodal NK-T-Cell; Lymphoma, T-Cell; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms; Plaque psoriasis; Psoriasis; Rejection of renal transplantation; Rejection of liver transplantation; Renal Insufficiency | Details |
| SBT-11-5301 | SBT115301 | Phase 1 Clinical | Sonoma Biotherapeutics Inc | Autoimmune Diseases | Details |
| PIT-565 | PIT-565 | Phase 1 Clinical | Novartis Pharma Ag | Arthritis, Rheumatoid; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Neoplasms; Nephrosis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments cliniques
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