CD45RA

CD45RA Informations sur la molécule

Nom anglais	Leukocyte common antigen	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	7	Alias de la cible	PTPRC，T200，CD45，Protein Tyrosine Phosphatase， Receptor Type C，CD45 Antigen，L-CA，Protein Tyrosine Phosphatase， Receptor Type， C Polypeptide，Receptor-Type Tyrosine-Protein Phosphatase C，T200 Leukocyte Common Antigen，Leukocyte Common Antigen，T200 Glycoprotein，EC 3.1.3.48，CD45R，GP180，B220，LCA，LY5，Leukocyte Common Antigens，Protein Tyrosine Phosphatase Receptor Type C，EC:3.1.3.48
Phase de R&D la plus avancée	Phase 3 Clinical

Nom anglais	Leukocyte common antigen
Alias de la cible	PTPRC，T200，CD45，Protein Tyrosine Phosphatase， Receptor Type C，CD45 Antigen，L-CA，Protein Tyrosine Phosphatase， Receptor Type， C Polypeptide，Receptor-Type Tyrosine-Protein Phosphatase C，T200 Leukocyte Common Antigen，Leukocyte Common Antigen，T200 Glycoprotein，EC 3.1.3.48，CD45R，GP180，B220，LCA，LY5，Leukocyte Common Antigens，Protein Tyrosine Phosphatase Receptor Type C，EC:3.1.3.48
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	7
Phase de R&D la plus avancée	Phase 3 Clinical

CD45RA Liste de produits

Attribut
Protein (1)Antibody (1)
Bibliothèque de produits
En ligne (2)
Espèces
Human (1)Mouse (1)
Étiquette
His Tag (1)- (1)
Marqueur
Unconjugated (1)PE Labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
CD5-H52H9	Human	HEK293	Human CD45RA / PTPRC protein, His Tag				Ajouter au panier
FABm040-01	Mouse	-	PE-Labeled Monoclonal Anti-Human CD45RA Antibody, Mouse IgG2b (AS624) (0.03% Proclin)				Ajouter au panier

Quantité totale2

CD45RAContexte de la molécule

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

CD45RAAlias de la molécule

B220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Immunomodulatory progenitor cell therapy (Celixir)		Phase 3 Clinical	Celixir	Cardiomyopathies; Endomyocardial Fibrosis	Details
I-131-Apamistamab	BC8-I-131; BC-8; 131IBC8; I-131 BC-8	Phase 3 Clinical	Fred Hutchinson Cancer Research Center	Anemia, Refractory, with Excess of Blasts; Anemia, Sickle Cell; Anemia, Sideroblastic; Angioimmunoblastic T-cell Lymphoma; Burkitt Lymphoma; Graft vs Host Disease; Hematopoietic stem cell transplantation (HSCT); Hodgkin Disease; Intraocular Lymphoma; Leukemia; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia-Lymphoma, Adult T-Cell; Lymphoma; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Large-Cell, Immunoblastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Lymphomatoid Granulomatosis; Mycosis Fungoides; Myelodysplastic Syndromes; Neoplasms, Gonadal Tissue; Neoplastic Cells, Circulating; Pancytopenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sezary Syndro	Details
At 211 MAb BC8-B10		Phase 2 Clinical	Fred Hutchinson Cancer Research Center	Neoplasms	Details
211At-BC8-B10	211At-BC8-B10	Phase 2 Clinical	Fred Hutchinson Cancer Research Center, National Cancer Institute	Hematologic Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Details
CD45BE-HSPC cells therapy (Kite Pharma)		Phase 1 Clinical	Kite Pharma	Hodgkin Disease; Lymphoma, B-Cell; Lymphoma, T-Cell; Richter's Syndrome	Details
CART-45 cells therapy (Kite Pharma)		Phase 1 Clinical	Kite Pharma	Hodgkin Disease; Lymphoma, B-Cell; Lymphoma, T-Cell; Richter's Syndrome	Details
TSC-102	TSC-102-A03; TSC-102-A0301; TSC-102; TSC-102-A01	Phase 1 Clinical	TScan Therapeutics Inc	Hematologic Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Details