CD52

CD52 Informations sur la molécule

Nom anglais	CAMPATH-1 antigen	Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	5	Alias de la cible	Epididymis Secretory Sperm Binding Protein Li 171mP，CD52 Antigen (CAMPATH-1 Antigen)，Epididymal Secretory Protein E5，He5，CDW52 Antigen (CAMPATH-1 Antigen)，CD52 Antigen，HEL-S-171mP，EDDM5，CD52，CDw52，Cambridge pathology 1 antigen，Human epididymis-specific protein 5，CAMPATH-1 antigen，CD52 Molecule
Phase de R&D la plus avancée	Approved

Nom anglais	CAMPATH-1 antigen
Alias de la cible	Epididymis Secretory Sperm Binding Protein Li 171mP，CD52 Antigen (CAMPATH-1 Antigen)，Epididymal Secretory Protein E5，He5，CDW52 Antigen (CAMPATH-1 Antigen)，CD52 Antigen，HEL-S-171mP，EDDM5，CD52，CDw52，Cambridge pathology 1 antigen，Human epididymis-specific protein 5，CAMPATH-1 antigen，CD52 Molecule
Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	5
Phase de R&D la plus avancée	Approved

CD52 Liste de produits

Attribut
Protein (3)Antibody (2)
Bibliothèque de produits
En ligne (5)
Espèces
Human (5)
Étiquette
Fc Tag & Avi Tag (1)Fc Tag (1)His Tag & Avi Tag (1)- (2)
Marqueur
Biotin-labeled (2)Unconjugated (3)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT CD2-H82E8	Human	HEK293	Biotinylated Human CD52 Protein, His,Avitag™	Ajouter au panier
CD2-C263G1	Human	HEK293	Monoclonal Anti-CD52 Antibody, Human IgG1, premium grade	Ajouter au panier
CD2-C263GN	Human	HEK293	Monoclonal Anti-CD52 Antibody, Human IgG1, Research Grade	Ajouter au panier
CD2-H525a	Human	HEK293	Human CD52 Protein, Fc Tag	Ajouter au panier
CD2-H82F3	Human	HEK293	Biotinylated Human CD52 Protein, Fc,Avitag™	Ajouter au panier

Quantité totale5

CD52Contexte de la molécule

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs).ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.

CD52Alias de la molécule

CDW52,HE5,CD52,CAMPATH-1 antigen

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Alemtuzumab biosimilar (Zhangjiang Biotechnology)		Phase 2 Clinical	Shanghai Zhangjiang Biotechnology Co Ltd	Leukemia, Lymphocytic, Chronic, B-Cell	Details
ALLO-647	ALLO-647	Phase 2 Clinical	Allogene Therapeutics Inc	Carcinoma, Renal Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma	Details
Alemtuzumab Biosimilars(Cellectis)	CLLS-52; CLLS52	Phase 2 Clinical	Cellectis Sa	Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	Details
Recombinant anti-CD52 humanized monoclonal antibody (Lanzhou Institute Of Biological Products/Shanghai Taiyin Biotechnology)		Phase 1 Clinical	Lanzhou Institute Of Biological Products Co Ltd, Shanghai Taiyin Biotechnology Co Ltd	Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Leukemia, Prolymphocytic, T-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell	Details
Alemtuzumab biosimilar(BioXpress)	BX-1523; BXT-1523	Clinical	Bioxpress Therapeutics Sa	Leukemia, B-Cell; Multiple Sclerosis	Details

Informations sur les médicaments commercialisés

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Plus ancien nom de marque	Pays d'approbation le plus ancien	Indication la plus ancienne	Société d'approbation la plus ancienne	Date d'approbation la plus ancienne	Indication	Essai clinique
Alemtuzumab	LDP-03; GZ-402673	Approved	Bayer AG, Genzyme Corp	Campath, Lemtrada, MabCampath	United States	Multiple Sclerosis	Genzyme Corp	2001-05-07	Anemia, Aplastic; Anemia, Sickle Cell; Bone marrow transplant rejection; Diabetes Mellitus, Type 1; Fallopian Tube Neoplasms; Graft Rejection; Graft vs Host Disease; Hematologic Neoplasms; Hodgkin Disease; Kidney Diseases; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Prolymphocytic, T-Cell; Leukemia, T-Cell; Leukemia-Lymphoma, Adult T-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Mycosis Fungoides; Myelodysplastic Syndromes; Myositis, Inclusion Body; Ovarian Neoplasms; Pancytopenia; Peritoneal Neoplasms; Rejection of renal transplantation; Sezary Syndrome; Waldenstrom Macroglobulinemia	Details