CD59

CD59 Informations sur la molécule

Nom anglais	CD59 glycoprotein	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1	Alias de la cible	CD59 Antigens，Membrane attack complex inhibition factor，Membrane inhibitor of reactive lysis，MEM43 antigen，HRF-20，MIRL，20 kDa homologous restriction factor，MAC-inhibitory protein，MACIF，Protectin，MAC-IP，1F5 antigen，P18-20，CD59 Molecule， Complement Regulatory Protein，MSK21，CD59 Antigen， Complement Regulatory Protein，16.3A5，Lymphocytic Antigen CD59/MEM43，MIC11，MIN1，Ly-6-Like Protein，1F5，T Cell-Activating Protein，CD59 Antigen，EJ30，MIN2，MIN3，EL32，Surface Anitgen Recognized By Monoclonal Antibody 16.3A5，MEM43，EJ16，G344，CD59 Molecule (CD59 Blood Group)，Membrane Attack Complex (MAC) Inhibition Factor，CD59 Molecule，CD59 Antigen P18-20 (Antigen Identified By Monoclonal Antibodies 16.3A5， EJ16， EJ30， EL32 And G344)，Human Leukocyte Antigen MIC11，HRF20，CD59 Blood Group Antigen
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	CD59 glycoprotein
Alias de la cible	CD59 Antigens，Membrane attack complex inhibition factor，Membrane inhibitor of reactive lysis，MEM43 antigen，HRF-20，MIRL，20 kDa homologous restriction factor，MAC-inhibitory protein，MACIF，Protectin，MAC-IP，1F5 antigen，P18-20，CD59 Molecule， Complement Regulatory Protein，MSK21，CD59 Antigen， Complement Regulatory Protein，16.3A5，Lymphocytic Antigen CD59/MEM43，MIC11，MIN1，Ly-6-Like Protein，1F5，T Cell-Activating Protein，CD59 Antigen，EJ30，MIN2，MIN3，EL32，Surface Anitgen Recognized By Monoclonal Antibody 16.3A5，MEM43，EJ16，G344，CD59 Molecule (CD59 Blood Group)，Membrane Attack Complex (MAC) Inhibition Factor，CD59 Molecule，CD59 Antigen P18-20 (Antigen Identified By Monoclonal Antibodies 16.3A5， EJ16， EJ30， EL32 And G344)，Human Leukocyte Antigen MIC11，HRF20，CD59 Blood Group Antigen
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1
Phase de R&D la plus avancée	Phase 2 Clinical

CD59 Liste de produits

Attribut
Protein (2)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
His Tag (1)His Tag & Avi Tag (1)
Marqueur
Unconjugated (1)Biotin-labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
CD9-H52H9	Human	HEK293	Human CD59 Protein, His Tag				Ajouter au panier
CD9-H82E3	Human	HEK293	Biotinylated Human CD59 Protein, His,Avitag™				Ajouter au panier

Quantité totale2

CD59Contexte de la molécule

CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL. CD59 has been identified as a glycosylphosphatidylinositol-anchored membrane protein that acts as an inhibitor of the formation of the membrane attack complex to regulate complement activation. Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

CD59Alias de la molécule

CD59,16.3A5,1F5,EJ16,EJ30,EL32,FLJ38134,FLJ92039,G344,HRF20,MAC-IP,MACIF,MEM43,MGC2354,MIC11,MIN1,MIN2,MIN3,MIRL,MSK21,p18-20,Protectin

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Onzemipgene Parvec	HMR-59; AAVCAGsCD59; JNJ-81201887; JNJ-1887	Phase 2 Clinical	Tufts University	Geographic Atrophy; Macular Degeneration; Pyruvate kinase deficiency	Details