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CD8 alpha & beta

CD8 alpha & beta Informations sur la molécule

Nom anglaisT-cell surface glycoprotein CD8 beta chainNombre de médicaments commercialisés0
Nombre de médicaments cliniques0Alias de la cibleCD8b,CD8b Molecule
Phase de R&D la plus avancéePreclinical
Nom anglaisT-cell surface glycoprotein CD8 beta chain
Alias de la cibleCD8b,CD8b Molecule
Nombre de médicaments commercialisés0
Nombre de médicaments cliniques0
Phase de R&D la plus avancéePreclinical

CD8 alpha & betaContexte de la molécule

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.

CD8 alpha & betaAlias de la molécule

CD8 alpha & beta,CD8A & CD8B
  • Informations sur la molécule
  • Liste de produits